Outcomes of Targeted Temperature Management for In-Hospital and Out-Of-Hospital Cardiac Arrest: A Matched Case-Control Study Using the National Database of Taiwan Network of Targeted Temperature Management for Cardiac Arrest (TIMECARD) Registry

10 July 2021: Database Analysis

Yu-san Chien ^12BCDEF , Min-Shan Tsai ^3B , Chien-Hua Huang ^3A , Chih-Hung Lai ^4AB , Wei-Chun Huang ^5A , Lung Chan ^6AB , Li-Kuo Kuo ^12ADF*

DOI: 10.12659/MSM.931203

Med Sci Monit 2021; 27:e931203

Table 4B Predictors of good neurological outcome at hospital discharge among patients receiving targeted temperature control.

	Single-variate analysis				Multivariate analysis
	OR	95% CI		P value	OR	95% CI		P value
Pre-arrest CPC	0.705	0.511	0.972	0.033	0.270	0.070	1.043	0.058
Use of epinephrine during resuscitation	0.604	0.381	0.958	0.032	0.032	0.002	0.435	0.010
Best motor function at ROSC	12.000	1.560	92.287	0.017	11.765	2.203	62.500	0.004
Time from ROSC to initiation of TTM, hours	0.917	0.845	0.996	0.039
Time from ROSC to initiation of TTM ≥6 hours	0.400	0.155	1.031	0.058
Time to normothermia during rewarm phase of TTM, hours	0.975	0.954	0.996	0.022
Time to return normothermia ≥25 hours	0.308	0.100	0.944	0.039	0.231	0.049	1.087	0.064
New seizure during TTM	0.148	0.052	0.423	0.000	0.086	0.020	0.370	0.001
CPC – cerebral performance category; ROSC – return of spontaneous circulation.