10 July 2021>: Database Analysis
Outcomes of Targeted Temperature Management for In-Hospital and Out-Of-Hospital Cardiac Arrest: A Matched Case-Control Study Using the National Database of Taiwan Network of Targeted Temperature Management for Cardiac Arrest (TIMECARD) Registry
Yu-san Chien 12BCDEF , Min-Shan Tsai 3B , Chien-Hua Huang 3A , Chih-Hung Lai 4AB , Wei-Chun Huang 5A , Lung Chan 6AB , Li-Kuo Kuo 12ADF*DOI: 10.12659/MSM.931203
Med Sci Monit 2021; 27:e931203
Table 3 Comparison of targeted temperature management related variables and clinical outcomes between patients with IHCA and OHCA.
IHCA | (N=103) | OHCA | (N=103) | P value | ||
---|---|---|---|---|---|---|
Time from ROSC to TTM (hours), mean (SD) | 4.99 | 4.38 | 5.35 | 3.73 | 0.526 | |
Targeted temperature (°C) | 33.12 | 0.48 | 33.18 | 0.51 | 0.402 | |
Reach targeted temperature (%) | 99 | 96% | 103 | 100% | 0.840 | |
Cold saline induction (%) | 50 | 48.54% | 62 | 60.19% | 0.093 | |
Maintenance mode | Arctic sun (%) | 50 | 48.54% | 46 | 44.66% | 0.576 |
Intravenous cooling catheter (%) | 4 | 3.88% | 3 | 2.91% | 0.700 | |
Traditional ice blanket (%) | 39 | 37.86% | 48 | 46.60% | 0.204 | |
Complication | New bleeding (%) | 22 | 21.36% | 30 | 29.13% | 0.199 |
New arrhythmia (%) | 42 | 40.78% | 46 | 44.66% | 0.573 | |
New infection (%) | 51 | 49.51% | 46 | 44.66% | 0.485 | |
New seizure (%) | 28 | 27.18% | 34 | 33.01% | 0.362 | |
Hypokalemia (%) | 53 | 51.46% | 62 | 60.19% | 0.207 | |
Hypoglycemia (%) | 10 | 9.71% | 12 | 11.65% | 0.822 | |
Survival to completion of TTM (%) | 90 | 87.38% | 92 | 89.32% | 0.664 | |
Survival to ICU discharge (%) | 54 | 52.4% | 55 | 53.4% | 0.889 | |
CPC at ICU discharge, mean (SD) | 2.9 | 1.2 | 3.0 | 1.2 | 0.682 | |
ICU stay among survivors (days), mean (SD) | 25.8 | 18.4 | 19.5 | 14.2 | 0.048 | |
Survival to hospital discharge (%) | 44 | 42.7% | 44 | 42.7% | 1.000 | |
CPC at hospital discharge, mean (SD) | 2.5 | 1.3 | 2.7 | 1.2 | 0.593 | |
CPC ≤2 at ICU discharge (%) | 20 | 19.4% | 19 | 18.5% | 0.605 | |
CPC ≤2 at hospital discharge (%) | 20 | 19.4% | 14 | 12.7% | 0.246 | |
Hospital stay among survivors (days), mean (SD) | 46.2 | 30.7 | 48.3 | 34.0 | 0.770 | |
IHCA – in-hospital cardiac arrest; OHCA – out-of-hospital cardiac arrest; TTM – targeted temperature management; GCS – Glasgow Coma Scale; CPC – cerebral performance category. |