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10 July 2021: Database Analysis

Outcomes of Targeted Temperature Management for In-Hospital and Out-Of-Hospital Cardiac Arrest: A Matched Case-Control Study Using the National Database of Taiwan Network of Targeted Temperature Management for Cardiac Arrest (TIMECARD) Registry

Yu-san Chien 12BCDEF , Min-Shan Tsai 3B , Chien-Hua Huang 3A , Chih-Hung Lai 4AB , Wei-Chun Huang 5A , Lung Chan 6AB , Li-Kuo Kuo 12ADF*

DOI: 10.12659/MSM.931203

Med Sci Monit 2021; 27:e931203

Table 3 Comparison of targeted temperature management related variables and clinical outcomes between patients with IHCA and OHCA.

IHCA(N=103)OHCA(N=103)P value
Time from ROSC to TTM (hours), mean (SD)4.994.385.353.730.526
Targeted temperature (°C)33.120.4833.180.510.402
Reach targeted temperature (%)9996%103100%0.840
Cold saline induction (%)5048.54%6260.19%0.093
Maintenance modeArctic sun (%)5048.54%4644.66%0.576
Intravenous cooling catheter (%)43.88%32.91%0.700
Traditional ice blanket (%)3937.86%4846.60%0.204
ComplicationNew bleeding (%)2221.36%3029.13%0.199
New arrhythmia (%)4240.78%4644.66%0.573
New infection (%)5149.51%4644.66%0.485
New seizure (%)2827.18%3433.01%0.362
Hypokalemia (%)5351.46%6260.19%0.207
Hypoglycemia (%)109.71%1211.65%0.822
Survival to completion of TTM (%)9087.38%9289.32%0.664
Survival to ICU discharge (%)5452.4%5553.4%0.889
CPC at ICU discharge, mean (SD)
ICU stay among survivors (days), mean (SD)25.818.419.514.20.048
Survival to hospital discharge (%)4442.7%4442.7%1.000
CPC at hospital discharge, mean (SD)
CPC ≤2 at ICU discharge (%)2019.4%1918.5%0.605
CPC ≤2 at hospital discharge (%)2019.4%1412.7%0.246
Hospital stay among survivors (days), mean (SD)46.230.748.334.00.770
IHCA – in-hospital cardiac arrest; OHCA – out-of-hospital cardiac arrest; TTM – targeted temperature management; GCS – Glasgow Coma Scale; CPC – cerebral performance category.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750