13 June 2021: Clinical Research
Hemorheological Alteration in Patients with Cirrhosis Clinically Diagnosed with Portal Vein System Thrombosis After Splenectomy
Long Huang ABCEF* , Qingsheng Yu AEF , Hui Peng CDEDOI: 10.12659/MSM.931157
Med Sci Monit 2021; 27:e931157
Table 3 Receiver operating characteristic curve analysis for identifying the optimal cutoff values of influencing factors of portal vein system thrombosis after splenectomy.
| Variable | AUROC | P value | 95% CI | Cutoff value | Sensitivity | 1-Specificity |
|---|---|---|---|---|---|---|
| PT (s) | 0.553 | 0.53 | 0.390–0.715 | |||
| APTT (s) | 0.648 | 0.08 | 0.495–0.800 | |||
| FBG (g/L) | 0.493 | 0.93 | 0.331–0.654 | |||
| FDP (ug/mL) | 0.695 | 0.02 | 0.546–0.844 | 38.6 | 0.5 | 0.05 |
| D-dimer (mg/L) | 0.659 | 0.06 | 0.510–0.809 | |||
| High shear rate 200 (mPa.s) | 0.662 | 0.06 | 0.508–0.815 | |||
| Middle shear rate 50 (mPa.s) | 0.667 | 0.05 | 0.513–0.822 | 3.75 | 0.8 | 0.5 |
| Middle shear rate 30 (mPa.s) | 0.67 | 0.04 | 0.516–0.824 | 4.165 | 0.767 | 0.4 |
| Low shear rate 5 (mPa.s) | 0.671 | 0.04 | 0.515–0.826 | 6.705 | 0.8 | 0.45 |
| Low shear rate 1 (mPa.s) | 0.677 | 0.04 | 0.522–0.833 | 16.855 | 0.567 | 0.2 |
| Plasma viscosity (mPa.s) | 0.601 | 0.23 | 0.439–0.763 | |||
| ESR (mm/L) | 0.302 | 0.02 | 0.150–0.454 | 9 | 0.75 | 0.3 |
| Hematocrit (L/L) | 0.646 | 0.08 | 0.492–0.800 | |||
| Erythrocyte deformation index | 0.428 | 0.39 | 0.262–0.593 | |||
| Erythrocyte rigidity index | 0.469 | 0.71 | 0.303–0.636 | |||
| CI – confidence interval; PVST – portal vein system thrombosis; ROC – receiver operating characteristic; AUROC – area under the ROC curve; PT – prothrombin time; APTT – activated partial thromboplastin time; FBG – fibrinogen; FDP – fibrinogen degradation products; ESR – erythrocyte sedimentation rate | ||||||