13 June 2021: Clinical Research
Hemorheological Alteration in Patients with Cirrhosis Clinically Diagnosed with Portal Vein System Thrombosis After Splenectomy
Long Huang ABCEF* , Qingsheng Yu AEF , Hui Peng CDEDOI: 10.12659/MSM.931157
Med Sci Monit 2021; 27:e931157
Table 2 Comparison of coagulation function and hemorheology between the portal vein system thrombosis (PVST) group and control group (n=50, mean±standard deviation).
| Variable | PVST group (n=30) | Control group (n=20) | P value |
|---|---|---|---|
| PT (s) | 15.83±4.21 | 14.67±3.04 | 0.29 |
| APTT (s) | 44.70±13.76 | 37.58±5.97 | 0.04 |
| FBG (g/L) | 2.61±1.18 | 2.61±0.95 | 0.98 |
| FDP (ug/mL) | 40.91±27.47 | 22.77±8.14 | 0.01 |
| D-dimer (mg/L) | 12.87±7.13 | 9.13±3.65 | 0.04 |
| High shear rate 200 (mPa.s) | 3.48±0.45 | 3.24±0.34 | 0.05 |
| Middle shear rate 50 (mPa.s) | 4.14±0.53 | 3.85±0.43 | 0.05 |
| Middle shear rate 30 (mPa.s) | 4.55±0.59 | 4.23±0.48 | 0.05 |
| Low shear rate 5 (mPa.s) | 7.66±1.04 | 7.07±0.94 | 0.05 |
| Low shear rate 1 (mPa.s) | 16.75±2.48 | 15.31±2.30 | 0.04 |
| Plasma viscosity (mPa.s) | 1.58±0.12 | 1.54±0.10 | 0.19 |
| ESR (mm/L) | 11.17±12.01 | 17.55±11.61 | 0.07 |
| Hematocrit (L/L) | 0.41±0.05 | 0.38±0.04 | 0.04 |
| Erythrocyte deformation index | 0.66±0.06 | 0.68±0.06 | 0.20 |
| Erythrocyte rigidity index | 2.94±0.42 | 2.98±0.46 | 0.75 |
| PVST – portal vein system thrombosis; PT – prothrombin time; APTT – activated partial thromboplastin time; FBG – fibrinogen; FDP – fibrinogen degradation products; ESR – erythrocyte sedimentation rate. | |||