15 July 2021: Database Analysis
Epithelial Splicing Regulatory Protein 1 Is Overexpressed in Breast Cancer and Predicts Poor Prognosis for Breast Cancer Patients
Xinyu Liu 1ABCE , Qiangshan Wang 2B , Siqi Song 1B , Manman Feng 1B , Xiaoya Wang 1B , Ling Li 1B , Ying Liu 13B* , Chunying Shi 1BEG*DOI: 10.12659/MSM.931102
Med Sci Monit 2021; 27:e931102
Table 1 The significant changes of ESRPs expression in transcription level between different types of breast cancer and normal breast tissues (Oncomine database).
| Type of breast cancer versus normal breast tissue reference invasive breast carcinoma | Fold change | P Value | t-Test | Source and/or reference | |
|---|---|---|---|---|---|
| ESRP1 | Invasive ductal breast carcinoma epihelia | 2.250 | 3.79E-6 | 6.423 | Ma breast []28 |
| Ductal breast carcinoma in situ epithelia | 2.337 | 1.04E-5 | 6.140 | Ma breast []28 | |
| Intraductal cribriform breast adenocarcinoma | 4.225 | 8.09E-16 | 12.178 | TCGA breast | |
| Mixed lobular and ductal breast carcinoma | 2.985 | 3.56E-6 | 6.452 | TCGA breast | |
| Invasive lobular breast carcinoma | 3.120 | 1.21E-6 | 8.525 | TCGA breast | |
| Invasive breast carcinoma | 3.144 | 2.65E-15 | 9.426 | TCGA breast | |
| Invasive ductal breast carcinoma | 3.933 | 5.32E-19 | 12.204 | TCGA breast | |
| Ductal breast carcinoma | 3.178 | 1.72E-6 | 6.230 | Richardson breast []29 | |
| Invasive ductal breast carcinoma | 2.390 | 3.67E-5 | 7.168 | Zhao breast []30 | |
| ESRP2 | NA | NA | NA | NA | NA |
| NA – not available; TCGA – The Cancer Genome Atlas. | |||||