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19 March 2021: Clinical Research

Association Between Body Mass Index and Thyroid Function in Euthyroid Chinese Adults

Jing Fu 1ACE , Lin Zhang 1BDF , Yu An 1C , Yan Duan 1B , Jia Liu 1ADE* , Guang Wang 12AF*

DOI: 10.12659/MSM.930865

Med Sci Monit 2021; 27:e930865

Table 3 Logistic regression analyses of the risk of higher levels of indices for thyroid function.

OR95% CIP valueOR95% CIP value
Model 1
 Normal weightRefRef
 Overweight1.1510.932–1.4210.1921.279* 1.035–1.5810.022
 Obesity1.624** 1.145–2.3020.0071.778** 1.254–2.5210.001
Model 2
 Normal weightRefRef
 Overweight1.1380.921–1.4070.2321.350** 1.082–1.6840.008
 Obesity1.609** 1.133–2.2850.0081.871** 1.294–2.7070.001
Model 1
 Normal weightRefRef
 Overweight0.9550.774–1.1790.6701.390** 1.125–1.7180.002
 Obesity0.8040.568–1.1370.2172.080** 1.454–2.976
Model 2
 Normal weightRefRef
 Overweight0.9720.785–1.2050.7991.415** 1.144–1.7500.001
 Obesity0.7930.556–1.1290.1982.118** 1.478–3.037
TSH – thyroid-stimulating hormone; FT3 – free triiodothyronine; FT4 – free thyroxine. Normal weight: body mass index (BMI) 18.5 to 23.9 kg/m. Overweight: BMI 24.0 to 27.9 kg/m. Obese: BMI ≥28 kg/m. The dividing point for serum thyrotropin (TSH) was 1.52 mIU/L; for FT3, it was 5.33 pmol/L; for FT4, it was 16.36 pmol/L; and for FT3/FT4, it was 0.33. Model 1: Odds ratio (OR) and 95% confidence interval (CI) were calculated using logistic regression models without adjustment for variables. Model 2: OR and 95% CI were calculated using logistic regression models and adjusted for age and sex.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750