22 July 2021>: Database Analysis
Identification of Key Genes and Underlying Mechanisms in Acute Kawasaki Disease Based on Bioinformatics Analysis
Side Gao BCDEF , Wenjian Ma BCD , Xuze Lin BCD , Sizhuang Huang BC , Mengyue Yu AG*DOI: 10.12659/MSM.930547
Med Sci Monit 2021; 27:e930547
Supplementary Table 3 The top 10 results of KEGG pathway analyses of the shared DEGs.
KEGG term | Count | Gene | P value |
---|---|---|---|
hsa04380: Osteoclast differentiation | 11 | SOCS3, SPI1, NCF4, SIRPA, LILRB2, LILRB3, LILRA2, MAPK14, LILRA3, OSCAR, LILRA5 | 8.53E-06 |
hsa04640: Hematopoietic cell lineage | 9 | CD2, CSF3R, CR1, CD8A, ANPEP, ITGA2B, CD3G, IL7R, CD55 | 1.85E-05 |
hsa04668: TNF signaling pathway | 7 | SOCS3, CEBPB, MLKL, MAPK14, MMP9, IL18R1, CREB5 | 0.002972 |
hsa05134: Legionellosis | 5 | CR1, NLRC4, TLR5, MYD88, HSPA1A | 0.003569 |
hsa05321: Inflammatory bowel disease (IBD) | 4 | STAT4, RORA, TLR5, IL18R1 | 0.027762 |
hsa05140: Leishmaniasis | 4 | CR1, NCF4, MAPK14, MYD88 | 0.036063 |
hsa00500: Starch and sucrose metabolism | 3 | HK3, MGAM, PYGL | 0.036499 |
hsa05152: Tuberculosis | 6 | CEBPB, CR1, ITGAX, MAPK14, CAMP, MYD88 | 0.04376 |
hsa05034: Alcoholism | 6 | HIST2H2AA4, HIST1H3F, HIST1H2BD, HIST2H2BE, HIST2H2AC, CREB5 | 0.04376 |
hsa05132: Salmonella infection | 4 | NLRC4, MAPK14, TLR5, MYD88 | 0.049876 |