06 May 2021: Clinical Research
Establishment and Verification of a Prediction Model for Symptomatic Radiation Pneumonitis in Patients with Esophageal Cancer Receiving Radiotherapy
Liu-Ting Yang 1ABCDEFG , Lei Zhou 1BC , Long Chen 1ACDE , Shi-Xiong Liang 1ADE , Jiang-Qiong Huang 1DEF , Xiao-Dong Zhu 12ACDEF*DOI: 10.12659/MSM.930515
Med Sci Monit 2021; 27:e930515
Table 4 Univariate analysis of nutritional parameters and coagulation function in predicting symptomatic radiation pneumonitis.
| RP of grade <2 | RP of grade ≥2 | P value | |
|---|---|---|---|
| Albumin before RT | 38.18±3.79 | 36.96±4.18 | 0.129 |
| Albumin during RT | 34.22±3.66 | 33.28±3.398 | 0.218 |
| Albumin at the end of RT | 34.62±4.31 | 30.92±4.94 | 0.000 |
| Pre/end ratio of pre-albumin | 1.11±0.15 | 1.22±0.20 | 0.009 |
| Pre-albumin before RT | 211.80±59.52 | 193.84±60.07 | 0.145 |
| Pre-albumin during RT | 183.63±65.78 | 158.77±64.35 | 0.076 |
| Pre-albumin at the end of RT | 182.07±70.03 | 123.53±61.39 | 0.000 |
| Pre/end ratio of pre-albumin | 1.31±0.54 | 2.04±1.36 | 0.007 |
| BMI before RT | 21.20±3.16 | 21.48±3.02 | 0.674 |
| BMI at the end of RT | 20.50±2.78 | 20.08±2.82 | 0.475 |
| Pre/end BMI | 1.04±0.10 | 1.07±0.10 | 0.134 |
| D-Dimer before RT | 0.82±2.16 | 0.77±0.94 | 0.898 |
| D-Dimer at the end of RT | 1.10±1.37 | 2.42±3.26 | 0.046 |
| Fibrinogen before RT | 4.01±1.28 | 3.83±1.02 | 0.487 |
| Fibrinogen at the end of RT | 3.94±1.37 | 4.28±1.72 | 0.278 |
| RT – radiation therapy; BMI – body mass index. | |||