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07 September 2021: Clinical Research

Clinical Observation of Prophylactic Extended-Field Intensity-Modulated Radiation Therapy with Synchronous Chemotherapy in Locally Advanced Cervical Cancer

Xue Huang 1ABCDEFG , Mingming Fang 2BCF , Lin Zhu 1BCDF , Cheng Gu 2ABG , Han Cui 3BCDG , Chun Yang 4ACDF* , Yuxing Yang 1ABDF*

DOI: 10.12659/MSM.930457

Med Sci Monit 2021; 27:e930457

Table 3 There were 10 patients (58.82%) with III–IV degree myelosuppression in the extended-field group and 3 patients (17.65%) with III–IV degree myelosuppression in the pelvic-field group; the difference was statistically significant (P=0.0324). There were no significant differences between the 2 groups in the occurrence of radiation enteritis and radiation cystitis.

GroupMyelosuppressionRadiation enteritisRadiation cystitis
I+IIIII+IVI+IIIII+IVI+IIIII+IV
Extended-field group (n=17)7 (41.18%)10 (58.82%)15 (88.24%)2 (11.76%)17 (100.00%)0 (0.00%)
Pelvic-field group (n=17)14 (82.35%)3 (17.65%)17 (100.00%)0 (0.00%)17 (100.00%)0 (0.00%)
value (Fisher)0.03240.48481

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750