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15 April 2021: Clinical Research

Persistent Somatic Symptom Burden and Sleep Disturbance in Patients with COVID-19 During Hospitalization and After Discharge: A Prospective Cohort Study

Shujie Huang 12ABCDE* , Weitao Zhuang 12ABDEF* , Dongya Wang 34BDF , Lulu Zha 34BD , Xi Xu 34BCD , Xiangdong Li 34BF , Qiuling Shi 5CDE , Xin Shelley Wang 6CDE , Guibin Qiao 17A*

DOI: 10.12659/MSM.930447

Med Sci Monit 2021; 27:e930447

Table 1 Clinicopathological characteristics of COVID-19 patients.

Clinicopathological characteristicsn (%)
 Male44 (59.46)
 Female30 (40.54)
52.3±13.3
 Shortness of breath27 (36.5)
 Muscle pain15 (20.3)
 Fever54 (73.0)
 Chills6 (8.1)
 Fatigue22 (29.7)
 Headache3 (4.1)
 Dry mouth1 (1.35)
 Sore throat1 (1.35)
 Dyspnea5 (6.8)
 Cough (sputum production)32 (43.2)
 Dry cough18 (24.3)
 Palpitation3 (4.1)
 Chest tightness10 (13.5)
 Chest pain3 (4.1)
 Nausea2 (2.7)
 Diarrhea5 (6.8)
23.7±13.7
 Moderate cases60 (81.08)
 Severe cases14 (18.92)
 Hypertension21 (28.38)
 Aneurysm1 (1.35)
 Hyperlipidemia2 (2.70)
 Coronary atherosclerotic heart disease3 (4.05)
 Cardiac insufficiency1 (1.35)
 Bradycardia1 (1.35)
 DVT1 (1.35)
 Hypothyroidism2 (2.70)
 Diabetes mellitus type II11 (14.86)
 Bulla3 (4.05)
 COPD2 (2.70)
 Lung cancer1 (1.35)
 Hyperuricemia1 (1.35)
 Gouty arthritis1 (1.35)
 Chronic gastritis1 (1.35)
 Fatty liver2 (2.70)
 Hepatitis B3 (4.05)
 Gallstone1 (1.35)
 Kidney cyst1 (1.35)
 Chronic Kidney disease1 (1.35)
 Kidney cancer1 (1.35)
 Breast cancer1 (1.35)
21 (12.0–34.3)
 No13 (17.57)
 Yes61 (82.43)
 No71 (95.95)
 Yes3 (4.05)
 No68 (91.89)
 Yes6 (8.11)
 No32 (43.24)
 Yes42 (56.76)
 No43 (58.11)
 Yes31 (41.89)
 No61 (82.43)
 Yes13 (17.57)
 No46 (62.2)
 Yes28 (37.8)
 WBC (×10/L)6.14±1.94
 RBC (×10/L)4.14±0.59
 Hemoglobin (g/L)128.36±16.92
 Platelet (×10/L)244.14±78.69
 Neutrophil (×10/L)3.98±1.80
 Lymphocyte (×10/L)1.55±0.57
 Monocyte (×10/L)0.46±0.17
 Eosinophil (×10/L)0.12±0.11
 Basophil (×10/L)0.02±0.01
 C-reactive protein (mg/L)14.65±33.03
 hs-C-reactive protein (mg/L)3.00±2.49
 PCT (ng/ml)0.07±0.09
 SARS-CoV-IgM antibody76.46±97.14
 SARS-CoV-IgG-antibody143.97±46.11

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750