20 August 2021: Clinical Research
Association of Plasma Pro-Brain-Derived Neurotrophic Factor (proBDNF)/Mature Brain-Derived Neurotrophic Factor (mBDNF) Levels with Gene Val66Met Polymorphism in Alcohol Dependence
Min Mo 1BCDEG* , Xi-yue Fu 2BCDF* , Xu-lan Zhang 1BD , Shao-chuan Zhang 1BD , Hai-qing Zhang 1CD , Li Wu 1AF , Jia-lei Li 1AF , Li Zhou 1ACEFG*DOI: 10.12659/MSM.930421
Med Sci Monit 2021; 27:e930421
Table 1 Genotype distributions of rs6265 in alcohol-dependent patients and controls.
| N | Genotype (N, frequency%) | Allele (N, frequency%) | ||||
|---|---|---|---|---|---|---|
| Val/Val | Val/Met | Met/Met | Val | Met | ||
| Patients | 59 | 17 (28.81) | 33 (55.93) | 9 (15.26) | 67 (56.80) | 51 (43.20) |
| Controls | 37 | 8 (21.62) | 20 (54.05) | 9 (24.33) | 36 (48.60) | 38 (51.40) |
| χ | 1.46 | 1.21 | ||||
| 0.48 | 0.27 | |||||
| was calculated by Pearson chi-squared test. | ||||||