18 June 2021: Clinical Research
Relationship of Bone Status with Serum Uric Acid and Bilirubin in Men with Type 2 Diabetes: A Cross-Sectional Study
Yang Wu 1ABCDEF* , Shoukui Xiang 1BCDE* , Xiaohong Jiang 1B , Long Wang 1BF , Kun Wang 2AG* , Fei Hua 1AG*DOI: 10.12659/MSM.930410
Med Sci Monit 2021; 27:e930410
Table 1 Characteristics of the participants.
| Characteristics | All (n=631) | T-score ≥-1 (n=257) | T-score <−1 (n=374) | P |
|---|---|---|---|---|
| Age (years) | 57.3±12.0 | 56.6±11.9 | 57.8±12.1 | 0.217 |
| BMI (kg/m) | 24.9±3.6 | 26.0±4.0 | 24.2±3.1 | 0.000 |
| Diabetes duration (years) | 8.4±7.8 | 8.4±7.5 | 8.4±8.1 | 0.996 |
| HbA1c (%) | 9.7±2.4 | 9.6±2.2 | 9.7±2.5 | 0.611 |
| FBG (mmoL/L) | 9.1±3.2 | 9.1±3.2 | 9.1±3.3 | 0.968 |
| Insulin or analog use, n (%) | 235 (37.2) | 102 (16.2) | 133 (21.1) | 0.475 |
| Hypertension, (n%) | 371 (58.8) | 163 (25.8) | 208 (33.0) | 0.050 |
| Current smoker, n (%) | 296 (46.9) | 112 (17.7) | 184 (29.2) | 0.165 |
| Drinking habits, n (%) | 211 (33.4) | 93 (14.7) | 118 (18.7) | 0.378 |
| Total cholesterol (nmoL/L) | 4.5±1.2 | 4.5±1.3 | 4.4±1.1 | 0.434 |
| Triglycerides (nmoL/L) | 2.4±2.4 | 2.4±2.2 | 2.3±2.4 | 0.633 |
| HDL (nmoL/L) | 1.0±0.2 | 1.0±0.2 | 1.0±0.2 | 0.928 |
| LDL (nmoL/L) | 2.6±0.9 | 2.6±0.8 | 2.5±0.8 | 0.943 |
| Albumin | 39.7±4.9 | 39.8±4.0 | 39.6±5.5 | 0.611 |
| Creatinine (μmoL/L) | 76.4±14.7 | 77.8±14.1 | 75.4±15.1 | 0.043 |
| Uric acid (μmoL/) | 323.7±84.4 | 339.9±86.9 | 312.7±80.9 | 0.000 |
| TBIL (mmol/l) | 11.7±3.9 | 12.1±4.1 | 11.5±3.8 | 0.079 |
| 25(OH) D3 (ng/ml) | 18.6±7.9 | 19.4±8.2 | 18.1±7.7 | 0.146 |
| Calcium (mmol/l) | 2.3±0.1 | 2.3±0.1 | 2.3±0.1 | 0.336 |
| Phosphorus (mmol/l) | 1.2±0.2 | 1.2±0.2 | 1.2±0.2 | 0.445 |
| TH BMD | −0.5±0.8 | 0.1±0.6 | −0.9±0.7 | 0.000 |
| FN BMD | −1.1±0.9 | −0.5±0.7 | −1.5±0.7 | 0.000 |
| LV BMD | −0.8±1,3 | 0.2±0.9 | −1.5±1.0 | 0.000 |
| OC (ng/ml) | 11.4±4.4 | 10.6±3.7 | 12.0±4.7 | 0.000 |
| PINP (ng/ml) | 37.8±15.2 | 35.1±13.6 | 39.7±16.0 | 0.000 |
| CTX (pg/ml) | 415.0±224.1 | 366.8±198.7 | 448.1±234.6 | 0.000 |
| PTH (pg/ml) | 36.5±14.1 | 36.6±14.6 | 36.5±13.8 | 0.913 |
| BMI – body index; HbA1c – glycosylated hemoglobin; FBG – fasting blood glucose; HDL – high-density lipoprotein; LDL – low-density lipoprotein; TBIL – total bilirubin; TH – total hip; FN – femoral neck; LV – lumbar vertebral; BMD – bone mineral density; OC – osteocalcin; PINP – amino-terminal propeptide of type I procollagen; CTX – type I collagen carboxy-terminal peptide; PTH – parathyroid hormone. | ||||