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09 July 2021: Clinical Research

Secondary Immunodeficiency and Hypogammaglobulinemia with IgG Levels of <5 g/L in Patients with Multiple Myeloma: A Retrospective Study Between 2012 and 2020 at a University Hospital in China

Chunmei Ye 12BCEF* , Weiwei Chen 3EF* , Qi Gao 12B , Yanxia Chen 4B , Xiaolu Song 5B , Sujie Zheng 2C* , Jinlin Liu 2AEG*

DOI: 10.12659/MSM.930241

Med Sci Monit 2021; 27:e930241

Table 3 Clinical characteristics of multiple myeloma patients with and without secondary immunodeficiency.

IgG <5 g/L (n=45)IgG ≥5 g/L (n=103)
 Male34 (75.56)63 (61.17)
 Female11 (24.44)40 (38.83)
 ≤65 years23 (51.11)51 (49.51)
 >65 years22 (48.89)52 (50.49)
 IgA, λ light chain15 (33.33)11 (10.68)
 IgA, κ light chain12 (26.67)3 (2.91)
 IgD, λ light chain5 (11.11)4 (3.88)
 IgG, λ light chain1 (2.22)35 (33.98)
 IgG, κ light chain0 (0.00)25 (24.27)
 λ light chain6 (13.33)6 (5.83)
 κ light chain4 (8.89)8 (7.77)
 IgA0 (0.00)1 (0.97)
 IgG0 (0.00)1 (0.97)
 IgG, IgA, λ light chain0 (0.00)1 (0.97)
 Unknown2 (4.44)8 (7.77)
All the data were presented with no. (%).

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750