Different Doses of Nalbuphine Combined with Dexmedetomidine in Laparoscopic Oophorocystectomy

24 August 2021: Clinical Research

Xiaofen Liu ^ABCDEF , Jie Song ^BCDF , Yang Zhang ^BCDF , Ye Zhang ^BCDF , Xianwen Hu ^CDFG*

DOI: 10.12659/MSM.930197

Med Sci Monit 2021; 27:e930197

Table 2 VAS scores and PCIA pressing times within 48 h after surgery in all patients.

	Variables	LND, n=55	MND n=54	HND, n=55	Control, n=55	P value
Rest	VAS at 2 h	3.24±0.89^c	3.03±0.59^c	2.61±0.49^a	4.24±0.93^a
	VAS at 8 h	3.00±0.60^b	2.49±0.31^a	2.14±0.32^a	3.80±0.78^a
	VAS at 12 h	2.07±0.52^c	1.93±0.36^c	1.50±0.33^a	2.96±0.71^a
	VAS at 24 h	1.51±0.28^b	1.24±0.47^a	1.05±0.33^a	2.28±0.45^a
	VAS at 48 h	1.10±0.32	1.08±0.33	1.05±0.31	1.05±0.32	0.849
Cough	VAS at 2 h	4.44±0.83^b	3.87±0.64^a	3.20±0.57^a	5.14±1.16^a
	VAS at 8 h	4.12±0.62^b	3.37±0.74^a	2.74±0.72^a	4.53±0.94^a
	VAS at 12 h	2.93±0.64^b	2.57±0.61^a	2.18±0.50^a	3.55±0.85^a
	VAS at 24 h	2.02±0.54^b	1.43±0.51^a	1.29±0.52^a	2.84±0.52^a
	VAS at 48 h	1.45±0.35	1.44±0.34	1.46±0.37	1.51±0.38	0.799
	PCIA	2.18±1.09^c	2.16±0.90^c	1.57±0.49^a	3.16±1.31^a
^a ^b ^c ^d LND – low-dose nalbuphine and dexmedetomidine; MDN – middle-dose nalbuphine and dexmedetomidine; HND – high-dose nalbuphine and dexmedetomidine; PCIA – patient-controlled intravenous analgesia pump.