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22 May 2021: Clinical Research

Association of Lymphocyte-to-Monocyte Ratio with Poststroke Depression in Patients with Acute Ischemic Stroke

Lining Chong 1ACDF , Lin Han 2ABDF , Ruqian Liu 1BDF , Guomei Ma 1BF , Hao Ren 1ABCDEF*

DOI: 10.12659/MSM.930076

Med Sci Monit 2021; 27:e930076

Table 5 Ordinal multinomial logistic regression analysis for the association between lymphocyte-to-monocyte ratio (LMR) values and poststroke depression (PSD) severity.

TertileOR*95% CIp-Value
UnadjustedMiddle2.0261.164–3.5250.013
Lowest4.8992.899–8.265
Model 1a Middle2.0301.127–3.6580.018
Lowest2.7821.514–5.1090.001
Model 2b Middle1.9441.089–3.4730.025
Lowest2.6201.468–4.6740.001
Model 3c Middle1.8831.059–3.3500.031
Lowest2.6331.484–4.6650.001
OR – odds radio; CI – confidence interval; LMR – lymphocyte-to-monocyte ratio; PSD – post-stroke depression.
* Reference OR (1.000) is the highest tertile of LMR for PSD severity;
a adjusted for age, gender, marital status, admission to hospital, education years, smoking, alcohol drinking, hyperlipidemia, atrial fibrillation, cornary heart disease, C-reactive protein, erythrocyte sedimentation rate, procalcitonin and stroke history;
b adjusted for covariates from Model 1 and further adjusted for hypertension and diabetes;
c adjusted for covariates from Model 2 and further adjusted for NIHSS score on admission.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750