Association of Lymphocyte-to-Monocyte Ratio with Poststroke Depression in Patients with Acute Ischemic Stroke

22 May 2021: Clinical Research

Lining Chong ^1ACDF , Lin Han ^2ABDF , Ruqian Liu ^1BDF , Guomei Ma ^1BF , Hao Ren ^1ABCDEF*

DOI: 10.12659/MSM.930076

Med Sci Monit 2021; 27:e930076

Table 4 Binary logistic regression analysis for the association between lymphocyte-to-monocyte ratio (LMR) and poststroke depression (PSD).

	Tertile	OR*	95% CI	p-Value
Unadjusted	Middle	1.998	1.147–3.481	0.015
Unadjusted	Lowest	4.820	2.843–6.172
Model 1^a	Middle	1.946	1.083–3.499	0.026
Model 1^a	Lowest	3.105	1.689–5.709
Model 2^b	Middle	1.791	1.016–3.156	0.044
Model 2^b	Lowest	2.738	1.531–4.896	0.001
Model 3^c	Middle	1.823	1.037–3.207	0.037
Model 3^c	Lowest	3.024	1.822–5.632
OR – odds radio; CI – confidence interval; LMR – lymphocyte-to-monocyte ratio; PSD – post-stroke depression. ^* Reference OR (1.000) is the highest tertile of LMR for PSD; ^a adjusted for gender, marital status, admission to hospital, education years, smoking, alcohol drinking, C-reactive protein, erythrocyte sedimentation rate, procalcitonin and comorbidities (hypertension, diabetes, hyperlipidemia, atrial fibrillation, cornary heart disease, stroke history); ^b adjusted for covariates from Model 1 and further adjusted for age; ^c adjusted for covariates from Model 2 and further adjusted for NIHSS score on admission.