18 August 2021>: Database Analysis
Genome-Wide Profiling of Alternative Splicing Signatures Associated with Prognosis and Immune Microenvironment of Hepatocellular Carcinoma
Zhikun Liu 12ABCDEF , Jiangwei Ye 13ABCDE , Abid Ali Khan 12ABCDEF , Jun Chen 12BCDE , Lin Zhou 2BCDE , Shusen Zheng 2ADE , Xiao Xu 12ADG*DOI: 10.12659/MSM.930052
Med Sci Monit 2021; 27:e930052
Supplementary Table 4 Univariate Cox analysis of clinical characteristics, the risk score (calculated from the final prognostic signatures), and immune clusters on OS.
Gene | HR | HRL | HRU | z | p Value |
---|---|---|---|---|---|
AFP | 1.653993774 | 1.056434456 | 2.589555265 | 2.199987808 | 0.02780776 |
Age | 1.271770756 | 0.889443854 | 1.818440646 | 1.317774264 | 0.187579226 |
Stage AJCC | 2.107983211 | 1.430332369 | 3.10668577 | 3.768730419 | 0.00016408 |
Histologic grade | 1.059471958 | 0.732110869 | 1.533211537 | 0.306358796 | 0.759331477 |
Gender | 0.865133606 | 0.601082437 | 1.245180546 | −0.779736726 | 0.435545857 |
Vascular invasion | 1.328948406 | 0.86835282 | 2.033855165 | 1.309826185 | 0.190254643 |
Margin resection status | 1.745645112 | 0.882323759 | 3.453694662 | 1.600338101 | 0.109523599 |
Risk | 9.152315299 | 5.69349323 | 14.71238692 | 9.141626433 | 6.15E-20 |
Clusters | 1.300562624 | 0.806020468 | 2.09853621 | 1.076559725 | 0.281677005 |
Clusters | 2.106204802 | 1.33911337 | 3.312713298 | 3.223708751 | 0.00126542 |