18 August 2021: Database Analysis
Genome-Wide Profiling of Alternative Splicing Signatures Associated with Prognosis and Immune Microenvironment of Hepatocellular Carcinoma
Zhikun Liu 12ABCDEF , Jiangwei Ye 13ABCDE , Abid Ali Khan 12ABCDEF , Jun Chen 12BCDE , Lin Zhou 2BCDE , Shusen Zheng 2ADE , Xiao Xu 12ADG*DOI: 10.12659/MSM.930052
Med Sci Monit 2021; 27:e930052
Supplementary Table 3 Univariate Cox analysis of clinical characteristics, the risk score (calculated from the final prognostic signatures) and immune clusters on RFS.
| Gene | HR | HRL | HRU | z | p Value |
|---|---|---|---|---|---|
| AFP | 1.390524915 | 0.978021476 | 1.977011329 | 1.836187514 | 0.066329929 |
| Age | 1.014730874 | 0.748808106 | 1.375090279 | 0.094313179 | 0.924860381 |
| Stage AJCC | 2.462564044 | 1.778316607 | 3.41009112 | 5.425900986 | 5.77E-08 |
| Histologic grade | 1.1159185 | 0.815391573 | 1.527209919 | 0.685114137 | 0.4932719 |
| Gender | 0.898447567 | 0.650983214 | 1.239982866 | −0.651448262 | 0.514757165 |
| Vascular invasion | 1.871740209 | 1.31309223 | 2.668061946 | 3.465997653 | 0.000528268 |
| Margin resection status | 1.690756072 | 0.89015302 | 3.211420994 | 1.604466361 | 0.108611294 |
| Risk | 2.664870571 | 1.951169754 | 3.639629586 | 6.162677632 | 7.15E-10 |
| Clusters | 1.384500013 | 0.926179904 | 2.069619818 | 1.586099147 | 0.11271682 |
| Clusters | 2.142740551 | 1.460186979 | 3.144348727 | 3.894597278 | 9.84E-05 |