18 May 2021>: Database Analysis
Identification of a DNA Methylation-Based Prognostic Signature for Patients with Triple-Negative Breast Cancer
Yinqi Gao 1ABCE , Xuelong Wang 2AC , Shihui Li 1CE , Zhiqiang Zhang 1CE , Xuefei Li 1CE , Fangcai Lin 1AE*DOI: 10.12659/MSM.930025
Med Sci Monit 2021; 27:e930025
Table 4 Univariate and multivariate Cox regression analysis in the training and validation cohorts.
Variables | Univariate analysis | Multivariate analysis | ||
---|---|---|---|---|
HR (95% CI) | P | HR (95% CI) | P | |
Age | ||||
≤60/>60 | 1.02 (0.31–3.33) | 0.970 | 0.64 (0.19–2.14) | 0.464 |
Stage | ||||
I+II/III+IV | 19.7 (4.17–93.4) | 1.7E-04 | 8.19 (1.22–55.2) | 0.031 |
Lymph node status | ||||
Non-metastasis/metastasis | 4.52 (1.24–16.5) | 0.022 | 3.77 (0.50–28.5) | 0.198 |
Risk score | ||||
Low/high | 6.54 (1.44–29.6) | 0.015 | 7.55 (1.39–40.9) | 0.019 |
Age | ||||
≤60/>60 | 1.33 (0.82–2.14) | 0.245 | 1.24 (0.76–2.01) | 0.394 |
Stage | ||||
I+II/III+IV | 2.65 (1.41–4.97) | 0.002 | 2.11 (1.09–4.09) | 0.026 |
Risk score | ||||
Low/high | 2.09 (1.28–3.44) | 0.003 | 1.77 (1.05–3.00) | 0.033 |
Age | ||||
≤60/>60 | 0.85 (0.45–1.62) | 0.616 | 0.66 (0.34–1.29) | 0.227 |
Risk score | ||||
Low/high | 2.42 (1.27–4.59) | 0.007 | 2.66 (1.38–5.11) | 0.003 |