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27 April 2021: Clinical Research

The Effects of Obesity on Mortality Following Coronary Artery Bypass Graft Surgery: A Retrospective Study from a Single Center in China

Mengwei Lv 12BDF* , Fei Gao 3BCD* , Ban Liu 4DEF* , Pratik Pandey 4EF , Yipeng Feng 5BC , Yingwei Wang 6BC , Yangyang Zhang 1ADFG* , Zhi Li 7ADE*

DOI: 10.12659/MSM.929912

Med Sci Monit 2021; 27:e929912

Table 1 Demographic and clinical variables for coronary artery bypass grafting (CABG) patients by body mass index (BMI) groups.

VariablesNormal (n=596)Overweight (n=684)Obese (n=191)P value
Male sex (n,%)465 (78.0)528 (77.2)142 (74.3)0.574
Age (y)66.36±8.0364.52±8.1161.75±9.55
BMI (kg/m)22.17±1.2825.75±1.1030.10±2.16
BSA (m)1.77±0.121.90±0.132.04±0.15
Types of CAD0.399
 Stable angina pectoris (n, %)197 (33.1)244 (35.7)65 (34.0)
 Unstable angina pectoris (n, %)302 (50.7)351 (51.3)103 (53.9)
 Acute myocardial infarction (n, %)97 (16.3)89 (13.0)23 (12.0)
Diabetes mellitus (n, %)188 (31.5)222 (32.5)68 (35.6)0.581
Hypertension (n, %)360 (60.4)495 (72.4)147 (77.0)
Cerebrovascular disease0.773
 Stroke (n, %)17 (2.9)20 (2.9)7 (3.7)
 Lacunar infarction (n, %)96 (16.1)115 (16.8)25 (13.1)
Peripheral vascular disease (n, %)15 (2.5)16 (2.3)3 (2.3)0.749
Preoperative atrial fibrillation (n, %)22 (3.7)13 (1.9)4 (2.1)0.121
Pulmonary hypertension (n, %)62 (10.4)68 (9.9)13 (6.8)0.332
Serum creatinine (μmol/l)83.31±45.8883.18±41.9581.42±34.910.858
Ccr (mL/min/1.73 m)71.13±21.6283.90±25.33101.81±31.87
Renal failure (n, %)13 (2.2)5 (0.7)1 (0.5)0.045
LVEF81 (13.6)68 (9.9)18 (9.4)0.081
Triple vessel disease (n, %)533 (89.4)616 (90.1)161 (84.3)0.145
COPD (n, %)15 (2.5)19 (2.8)4 (2.1)0.863
Previous PCI (n, %)37 (6.2)31 (4.5)11 (5.8)0.401
NYHA
 I (n, %)92 (15.4)69 (10.1)35 (18.3)
 II (n, %)375 (62.9)450 (65.8)122 (63.9)
 III (n, %)111 (18.6)158 (23.1)33 (17.3)
 IV (n, %)18 (3.0)7 (1.0)1 (0.5)
Off-pump CABG (n, %)426 (71.5)540 (78.9)164 (85.9)
In-hospital death (n, %)30 (5.0)9 (1.3)0 (0.0)
BMI – body mass index; BSA – body surface area; CAD – coronary artery disease; Ccr – creatinine clearance rate; LVEF – left ventricular ejection fraction; COPD – chronic obstructive pulmonary disease; PCI – percutaneous coronary intervention; NYHA – New York Heart Association; CABG – coronary artery bypass grafting.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750