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10 May 2021: Clinical Research

Type of Necrosis Influences Prognosis in Hepatocellular Carcinoma After the First Transarterial Chemoembolization

Zhi-Juan Wu 1BCDE , Yin-Fa Xie 2B , Xu Chang 2BCD , Lin Zhang 2AE* , Hui-Yong Wu 2B , Ji-Bing Liu 2B , Jian-Xin Zhang 2C , Peng Sun 2C

DOI: 10.12659/MSM.929884

Med Sci Monit 2021; 27:e929884

Table 4 Univariate and multivariate analyses of the factors affecting overall survival.

ParameterUnivariate analysisMultivariate analysis
Hazard ratio95% CIP valueHazard ratio95% CIP value
Necrosis type (liquefactive/coagulative)0.6230.450–0.8630.0040.5960.426–0.8340.003
Sex (Male/Female)1.3540.823–2.2260.231
Age (>60 years/1.2320.879–1.7270.226
Hepatitis (present/absent)0.9440.604–1.4740.799
Liver cirrhosis (present/absent)0.6070.439–0.8400.0020.6640.471–0.9360.019
Child-Pugh classification (B/A)0.1940.126–0.3000.0000.2100.134–0.3290.000
Barcelona Clinic Liver Cancer (stage C/stage B)0.7800.510–1.1930.250
Maximum diameter (>10 cm/0.9420.683–1.2990.715
Pseudocapsule (present/absent)0.9940.702–1.4080.972
Alpha-fetoprotein (>400 ng/ml/0.7930.571–1.0990.163
Location (left lobe/right lobe)0.6980.486–1.0050.0520.6750.461–0.9890.044
Portal vein tumor thrombus (present/absent)0.7000.501–0.9780.0360.9100.629–1.3150.615
Arteriovenous fistula (present/absent)0.6240.421–0.9250.0180.7290.481–1.1040.136
Other treatments (present/absent)0.7570.512–1.1210.163
CI – confidence interval.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750