Predicting the Risk of Acute Kidney Injury in Patients After Percutaneous Coronary Intervention (PCI) or Cardiopulmonary Bypass (CPB) Surgery: Development and Assessment of a Nomogram Prediction Model

25 April 2021: Clinical Research

Yi Du ^ABCDEFG , Xiu-Zhe Wang ^ABFG , Wei-Dong Wu ^ABCDE* , Hai-Peng Shi ^ABC , Xiao-Jing Yang ^CD , Wen-Jing Wu ^BC , Shu-Xian Chen ^EF

DOI: 10.12659/MSM.929791

Med Sci Monit 2021; 27:e929791

Table 2 Univariate and multivariate logistic regression.

Variable	Univariate analysis		Multivariate analysis
Variable	OR (95% CI)	P value	OR (95% CI)	P value
Operation, CPB	0.244 (0.134–0.444)		0.094 (0.032–0.279)
Age (year)	1.057 (1.031–1.084)		1.102 (1.055–1.151)
Hypertension	0.964 (0.539–1.721)	0.9	NA
Diabetes	0.787 (0.371–1.666)	0.531	NA
Hypercholesterolemia	0.573 (0.321–1.022)	0.059	NA
Cerebral vascular accident	1.745 (0.589–5.167)	0.315	NA
Chronic obstructive pulmonary diease	0.804 (0.092–7.013)	0.843	NA
Congestive heart failure	2.000 (1.112–3.594)	0.021	2.605 (1.004–6.758)	0.049
Betablockers	0.785 (0.410–1.503)	0.465	NA
Angiotensinaldosterone system antagonists	0.568 (0.294–1.097)	0.092	NA
Estimated glomerular filtration rate	1.224 (0.869–1.723)	0.247	NA
BMI, ≥26.7(kg/m)	0.247 (0.136–0.451)		0.339 (0.134–0.857)	0.022
Heart rate, ≥85/min	3.252 (1.799–5.880)		2.929 (1.135–7.558)	0.026
WBC count, ≥12.9×10/L	4.103 (2.251–7.477)		2.676 (1.045–6.854)	0.04
Platelet count, ≥174×10/L	0.117 (0.050–0.276)		0.061 (0.013–0.296)
Serum creatinine, ≥0.67 mg/dL	2.295 (0.780–6.749)	0.131	NA
Hemoglobin, ≥13.3 g/dL	0.191 (0.103–0.355)		0.226 (0.089–0.574)	0.002
Hemoglobin A1c, ≥4.39%	2.593 (0.762–8.830)	0.127	NA
Uric acid, ≥7.532 mg/dL	3.148 (1.716–5.777)		3.449 (1.213–9.806)	0.02
PI kidney cortex, ≥14.3 dB	0.200 (0.091–0.441)		0.170 (0.050–0.581)	0.005
PI Kidney with mass, ≥11.47 dB	0.137 (0.071–0.263)		0.149 (0.057–0.392)
CPB – cardiopulmonary bypass; PI – peak intensity; WBC – white blood cells.