05 June 2021>: Animal Study
Anti-Psoriatic Effects of Middle Fragment of Chlamydial Plasmid-Encoded Protein pGP3 in an Imiquimod-Induced Psoriasis Mouse Model
Yiming Zhang 1A* , Miaomiao Ma 2A* , Jun Li 3D , Yingye Wu 2C , Lu Xue 2C , Rongrong Zhao 2B , Lu Wang 2E , Shuping Hou 2G* , Huiping Wang 2G*DOI: 10.12659/MSM.929781
Med Sci Monit 2021; 27:e929781
Table 3 Comparison of epidermis thickness on day 8.
Group | Case | Epidermis thickness (μm) |
---|---|---|
Control | 8 | 10.03±1.51 |
IMQ | 8 | 94.26±19.45 |
IM-PBS | 8 | 89.83±16.56 |
IM-pGP3 | 8 | 70.15±12.89* |
IM-pGP3M | 8 | 69.59±13.94* |
IMQ – imiquimod; PBS – phosphate-buffered saline; IM – intramuscular. Epidermis was significantly thinner in mice treated with pGP3 and pGP3M than in mice treated with the IM-PBS group on day 8. Results are shown as mean±SD. * |