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05 June 2021: Animal Study

Anti-Psoriatic Effects of Middle Fragment of Chlamydial Plasmid-Encoded Protein pGP3 in an Imiquimod-Induced Psoriasis Mouse Model

Yiming Zhang 1A* , Miaomiao Ma 2A* , Jun Li 3D , Yingye Wu 2C , Lu Xue 2C , Rongrong Zhao 2B , Lu Wang 2E , Shuping Hou 2G* , Huiping Wang 2G*

DOI: 10.12659/MSM.929781

Med Sci Monit 2021; 27:e929781

Table 1 Experimental grouping.

NormalIMQIM-pGP3IM-pGP3MIM-PBS
IMQ\
pGP3\\pGP3\\
pGP3M\\\pGP3M\
IMQ – imiquimod; PBS – phosphate-buffered saline; IM – intramuscular. The mice were divided into 5 groups (8 mice/group): Normal group, not administered with drug or IMQ; IMQ group, administered with IMQ; IM-pGP3, administered with IMQ and intramuscularly injected with pGP3; IM-pGP3M, administered with IMQ and intramuscularly injected with pGP3M, IM-PBS, administered with IMQ and intramuscularly injected with phosphate-buffered saline (PBS).

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750