05 June 2021>: Animal Study
Anti-Psoriatic Effects of Middle Fragment of Chlamydial Plasmid-Encoded Protein pGP3 in an Imiquimod-Induced Psoriasis Mouse Model
Yiming Zhang 1A* , Miaomiao Ma 2A* , Jun Li 3D , Yingye Wu 2C , Lu Xue 2C , Rongrong Zhao 2B , Lu Wang 2E , Shuping Hou 2G* , Huiping Wang 2G*DOI: 10.12659/MSM.929781
Med Sci Monit 2021; 27:e929781
Table 1 Experimental grouping.
Normal | IMQ | IM-pGP3 | IM-pGP3M | IM-PBS | |
---|---|---|---|---|---|
IMQ | \ | √ | √ | √ | √ |
pGP3 | \ | \ | pGP3 | \ | \ |
pGP3M | \ | \ | \ | pGP3M | \ |
IMQ – imiquimod; PBS – phosphate-buffered saline; IM – intramuscular. The mice were divided into 5 groups (8 mice/group): Normal group, not administered with drug or IMQ; IMQ group, administered with IMQ; IM-pGP3, administered with IMQ and intramuscularly injected with pGP3; IM-pGP3M, administered with IMQ and intramuscularly injected with pGP3M, IM-PBS, administered with IMQ and intramuscularly injected with phosphate-buffered saline (PBS). |