Cross-Sectional Study of the Effects of Job Burnout on Immune Function in 105 Female Oncology Nurses at a Tertiary Oncology Hospital

04 May 2021: Clinical Research

Jing Cui ^ABCDEF , Yun-Hong Ren ^BCDE , Feng-Juan Zhao ^BCDE , Ying Chen ^BF , Ying-Fan Huang ^BF , Ling Yang ^BF , Xue-Mei You ^ABCDEFG*

DOI: 10.12659/MSM.929711

Med Sci Monit 2021; 27:e929711

Table 3 Correlation between immune variables and demographic data and burnout index.

Variables	Humoral immunity (g/L)			Complement (g/L)		Cellular immunity (/mm3) of [% to lymphocytes]
Variables	IgG	IgM	IgA	C3	C4	CD3+	CD4+	CD8+	CD4+/CD8+	NK	CD19+
EE	−0.022	−0.071	0.030	−0.014	0.071	−0.083	−0.001	−0.031	0.046	0.122	0.051
DP	−0.003	−0.098	0.001	0.206^a	0.345^b	−0.083	−0.033	−0.047	0.048	0.102	−0.101
PA	0.063	0.027	−0.089	−0.097	−0.138	0.016	−0.147	0.182	−0.242^a	−0.071	0.042
Age group	0.032	0.098	0.243^a	0.274^b	0.133	−0.084	0.032	−0.034	0.057	0.005	−0.172
Marital status	−0.178	0.004	−0.192^a	−0.265^b	−0.196	0.189	−0.080	0.165	−0.178	0.009	0.022
Fixed department	0.073	0.015	−0.203^a	−0.318^b	−0.335^b	0.158	−0.014	0.138	−0.107	−0.035	0.038
Length of service	−0.086	−0.010	0.158	0.186	0.049	−0.197^a	−0.044	−0.066	−0.021	−0.037	−0.094
Head nurse or above	0.198^a	−0.081	−0.225^a	−0.134	−0.178	0.029	0.017	−0.129	0.100	0.108	0.122
Number of responsible patients per day	0.095	−0.100	0.158	0.234^a	−0.022	0.003	0.094	−0.055	0.092	−0.058	0.198^a
M±S	14.725 ±2.357	1.501 ±0.592	2.423 ±0.780	1.011 ±0.162	0.205 ±0.065	68.442 ±6.879	36.008 ±0.832	26.077 ±0.558	1.450 ±0.414	12.043 ±5.603	11.050 ±3.630
^* Emotional exhaustion (EE), depersonalization (DP), personal accomplishment (PA),complement component 4 (C4),complement component 3 (C3). Statistical significance of the Spearman correlation coefficient: ^a ^b