06 September 2021>: Clinical Research
Effects of Cyanoacrylate in Rabbits with Induced Achilles Tendon Rupture
Mehmet Murat Bala 1AE* , Abdullah Alper Şahin 2B , Mehmet Boz 3C , Yasin Durukan 4D , Tülin Fırat 5E , Murat Pakdil 6F , Kutay Engin Özturan 7GDOI: 10.12659/MSM.929709
Med Sci Monit 2021; 27:e929709
Table 2 Comparisons of histopathological variables were conducted at week 4 and week 6.
Histopathological variables | Week 4 (n=16) | Week 6 (n=16) | ||||
---|---|---|---|---|---|---|
Control (n=8) | Experiment (n=8) | p* | Control (n=8) | Experiment (n=8) | p* | |
Granulation | 0 (0%) | 8 (100%) | ** | 1 (12.5%) | 7 (87.5%) | 0.010** |
Foreign body giant cell | 0 (0%) | 8 (100%) | ** | 0 (0%) | 7 (87.5%) | 0.001** |
Inflammation | 6 (75%) | 6 (75%) | 1.000 | 4 (50%) | 7 (87.5%) | 0.282 |
Neovascularization degree | ||||||
0 | 0 (0%) | 0 (0%) | 1.000 | 0 (0%) | 0 (0%) | 1.000 |
1 | 0 (0%) | 1 (12.5%) | 0 (0%) | 0 (0%) | ||
2 | 2 (25%) | 1 (12.5%) | 1 (12.5%) | 1 (12.5%) | ||
3 | 6 (75%) | 6 (75%) | 7 (87.5%) | 7 (87.5%) | ||
Fibrillary collagen alignment | ||||||
Irregular | 3 (37.5%) | 3 (37.5%) | 1.000 | 7 (87.5%) | 6 (75.0%) | 1.000 |
Regular | 5 (67.5%) | 5 (67.5%) | 1 (12.5%) | 2 (25.0%) | ||
Fibroblastic activity | ||||||
1 | 1 (12.5%) | 0 (0%) | 1.000 | 3 (37.5%) | 0 (0%) | 0.200 |
2 | 7 (87.5%) | 8 (100%) | 5 (67.5%) | 8 (100%) | ||
* Fisher’s exact test; ** statistically significant at α=0.05. |