11 February 2021>: Clinical Research
Effect of I Therapy on Complete Blood Count in Patients with Differentiated Thyroid Cancer
Zhongying Rui CDEF , Ruixin Wu BCD , Wei Zheng ADG* , Xuan Wang BDF , Zhaowei Meng AF , Jian Tan AFDOI: 10.12659/MSM.929590
Med Sci Monit 2021; 27:e929590
Table 4 CBC data before and after 131I therapy by age group and according to the number of treatment cycles and cumulative dose.
Mean±SD | Before | After (treatment cycles) | After (cumulative dose) | |||||
---|---|---|---|---|---|---|---|---|
One cycle | Two cycles | Three cycles | Four cycles | ≤5550 | 5551–11100 | >11100 | ||
WBCs, 10/L | ||||||||
6.43±1.71 | 6.08±1.60* | 5.96±1.31* | 6.07±1.78 | 6.58±1.44 | 6.09±1.60* | 5.94±1.49* | 6.26±1.83 | |
45–54 | 6.06±1.64 | 5.79±1.60 | 5.39±1.49* | 5.59±1.21 | 5.59±0.57 | 5.79±1.60 | 5.71±1.61 | 5.43±0.99 |
≥55 | 6.33±1.60 | 5.81±1.45* | 5.95±1.51* | 5.95±1.71 | 5.92±0.82 | 5.81±1.44* | 6.20±1.48 | 5.88±1.10 |
RBCs, 10/L | ||||||||
4.67±0.50 | 4.83±0.51* | 4.83±0.52* | 4.75±0.51* | 5.12±0.52* | 4.84±0.51* | 4.75±0.52* | 4.87±0.54* | |
45–54 | 4.67±0.40 | 4.84±0.43* | 4.75±0.43 | 4.93±0.41 | 5.01±0.47 | 4.84±0.43* | 4.75±0.48 | 4.83±0.47 |
≥55 | 4.62±0.46 | 4.75±0.53* | 4.72±0.50* | 4.73±0.45 | 4.86±0.50* | 4.75±0.53* | 4.66±0.50 | 4.84±0.49* |
Hb, g/L | ||||||||
135.69±19.74 | 144.13±88.43 | 140.97±18.31* | 140.26±19.30* | 144.60±21.93 | 138.01±22.91 | 160.35±158.93 | 139.27±20.16* | |
45–54 | 139.04±15.05 | 142.41±15.96* | 140.62±14.68 | 140.75±20.99* | 142.33±7.57 | 142.40±15.96* | 139.64±15.10 | 133.50±14.11 |
≥55 | 138.49±17.38 | 140.21±17.60 | 138.68±22.08 | 142.50±14.87* | 142.81±16.34* | 140.28±17.56 | 138.83±16.21 | 144.50±14.92* |
PLTs, 10/L | ||||||||
266.69±68.06 | 266.77±69.39 | 268.99±70.10 | 274.96±82.36 | 274.30±76.09 | 266.98±69.51 | 274.02±82.54 | 273.95±84.97 | |
45–54 | 260.02±58.10 | 253.88±57.08 | 261.84±67.12 | 229.00±54.40 | 276.67±43.82 | 253.38±57.51 | 258.79±67.73 | 257.50±64.51 |
≥55 | 246.33±67.96 | 242.10±71.81 | 239.87±69.98* | 231.75±60.32 | 234.63±64.63* | 242.26±71.59 | 242.23±69.46 | 222.57±55.17* |
Neutrophils, 10/L | ||||||||
4.56±6.05 | 4.23±4.53 | 4.45±5.89 | 3.96±1.49 | 4.32±0.91 | 4.23±4.54 | 3.78±1.12 | 4.21±1.43 | |
45–54 | 3.71±1.39 | 3.61±1.35 | 4.36±6.77 | 3.92±1.12 | 3.66±0.34 | 3.60±1.36 | 3.67±1.42 | 3.7917±0.95 |
≥55 | 3.85±1.21 | 3.97±4.65 | 8.71±37.25 | 3.93±1.48 | 3.79±0.52 | 3.97±4.64 | 4.03±1.24 | 3.82±1.00 |
Lymphocytes, 10/L | ||||||||
2.18±2.13 | 1.91±1.76 | 2.09±3.63 | 1.66±0.62* | 1.72±0.59 | 1.91±1.76 | 1.73±0.60* | 1.58±0.53* | |
45–54 | 1.91±0.60 | 1.73±0.48* | 2.21±5.05 | 1.29±0.38* | 1.53±0.32 | 1.74±0.48* | 1.58±0.44* | 1.31±0.33* |
≥55 | 2.01±0.81 | 1.80±0.73* | 1.76±0.59* | 1.55±0.63* | 1.68±0.57 | 1.79±0.73* | 1.71±0.75* | 1.61±0.54* |
Monocytes, 10/L | ||||||||
0.41±0.70 | 0.37±0.57 | 0.35±0.48 | 0.29±0.09 | 0.38±0.12 | 0.37±0.57 | 0.29±0.09 | 0.32±0.11 | |
45–54 | 0.29±0.08 | 0.29±0.08 | 0.39±0.79 | 0.27±0.05 | 0.28±0.05 | 0.29±0.08 | 0.29±0.07 | 0.25±0.05 |
≥55 | 0.30±0.11 | 0.35±0.62 | 0.32±0.24 | 0.30±0.13* | 0.28±0.06* | 0.35±0.62 | 0.28±0.11 | 0.28±0.09* |
Hb – hemoglobin; PLT – platelet; RBC – red blood cell; SD – standard deviation; WBC – white blood cell. * a Indicates an increase and b a decrease. |