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11 February 2021: Clinical Research

Effect of I Therapy on Complete Blood Count in Patients with Differentiated Thyroid Cancer

Zhongying Rui CDEF , Ruixin Wu BCD , Wei Zheng ADG* , Xuan Wang BDF , Zhaowei Meng AF , Jian Tan AF

DOI: 10.12659/MSM.929590

Med Sci Monit 2021; 27:e929590

Table 4 CBC data before and after 131I therapy by age group and according to the number of treatment cycles and cumulative dose.

Mean±SDBeforeAfter (treatment cycles)After (cumulative dose)
One cycleTwo cyclesThree cyclesFour cycles≤55505551–11100>11100
WBCs, 10/L
6.43±1.716.08±1.60* 5.96±1.31* 6.07±1.786.58±1.446.09±1.60* 5.94±1.49* 6.26±1.83
 45–546.06±1.645.79±1.605.39±1.49* 5.59±1.215.59±0.575.79±1.605.71±1.615.43±0.99
 ≥556.33±1.605.81±1.45* 5.95±1.51* 5.95±1.715.92±0.825.81±1.44* 6.20±1.485.88±1.10
RBCs, 10/L
4.67±0.504.83±0.51* 4.83±0.52* 4.75±0.51* 5.12±0.52* 4.84±0.51* 4.75±0.52* 4.87±0.54*
 45–544.67±0.404.84±0.43* 4.75±0.434.93±0.415.01±0.474.84±0.43* 4.75±0.484.83±0.47
 ≥554.62±0.464.75±0.53* 4.72±0.50* 4.73±0.454.86±0.50* 4.75±0.53* 4.66±0.504.84±0.49*
Hb, g/L
135.69±19.74144.13±88.43140.97±18.31* 140.26±19.30* 144.60±21.93138.01±22.91160.35±158.93139.27±20.16*
 45–54139.04±15.05142.41±15.96* 140.62±14.68140.75±20.99* 142.33±7.57142.40±15.96* 139.64±15.10133.50±14.11
 ≥55138.49±17.38140.21±17.60138.68±22.08142.50±14.87* 142.81±16.34* 140.28±17.56138.83±16.21144.50±14.92*
PLTs, 10/L
266.69±68.06266.77±69.39268.99±70.10274.96±82.36274.30±76.09266.98±69.51274.02±82.54273.95±84.97
 45–54260.02±58.10253.88±57.08261.84±67.12229.00±54.40276.67±43.82253.38±57.51258.79±67.73257.50±64.51
 ≥55246.33±67.96242.10±71.81239.87±69.98* 231.75±60.32234.63±64.63* 242.26±71.59242.23±69.46222.57±55.17*
Neutrophils, 10/L
4.56±6.054.23±4.534.45±5.893.96±1.494.32±0.914.23±4.543.78±1.124.21±1.43
 45–543.71±1.393.61±1.354.36±6.773.92±1.123.66±0.343.60±1.363.67±1.423.7917±0.95
 ≥553.85±1.213.97±4.658.71±37.253.93±1.483.79±0.523.97±4.644.03±1.243.82±1.00
Lymphocytes, 10/L
2.18±2.131.91±1.762.09±3.631.66±0.62* 1.72±0.591.91±1.761.73±0.60* 1.58±0.53*
 45–541.91±0.601.73±0.48* 2.21±5.051.29±0.38* 1.53±0.321.74±0.48* 1.58±0.44* 1.31±0.33*
 ≥552.01±0.811.80±0.73* 1.76±0.59* 1.55±0.63* 1.68±0.571.79±0.73* 1.71±0.75* 1.61±0.54*
Monocytes, 10/L
0.41±0.700.37±0.570.35±0.480.29±0.090.38±0.120.37±0.570.29±0.090.32±0.11
 45–540.29±0.080.29±0.080.39±0.790.27±0.050.28±0.050.29±0.080.29±0.070.25±0.05
 ≥550.30±0.110.35±0.620.32±0.240.30±0.13* 0.28±0.06* 0.35±0.620.28±0.110.28±0.09*
Hb – hemoglobin; PLT – platelet; RBC – red blood cell; SD – standard deviation; WBC – white blood cell.
*
a Indicates an increase and
b a decrease.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750