11 February 2021>: Clinical Research
Effect of I Therapy on Complete Blood Count in Patients with Differentiated Thyroid Cancer
Zhongying Rui CDEF , Ruixin Wu BCD , Wei Zheng ADG* , Xuan Wang BDF , Zhaowei Meng AF , Jian Tan AFDOI: 10.12659/MSM.929590
Med Sci Monit 2021; 27:e929590
Table 3 CBC data before and after 131I therapy by gender and according to the number of treatment cycles and cumulative dose.
Mean±SD | Before | After (treatment cycles) | After (cumulative dose) | |||||
---|---|---|---|---|---|---|---|---|
One cycle | Two cycles | Three cycles | Four cycles | ≤5550 | 5551–11100 | >11100 | ||
WBCs, 10/L | ||||||||
Male | 6.31±1.45 | 6.14±1.51 | 6.28±1.46* | 6.81±1.68 | 5.86±0.82 | 6.14±1.50 | 6.52±1.55 | 5.84±1.10 |
Female | 6.21±1.69 | 5.80±1.55* | 5.69±1.37* | 5.85±1.72* | 6.10±1.21 | 5.80±1.56* | 5.70±1.38* | 6.06±1.56 |
RBCs, 10/L | ||||||||
Male | 4.99±0.48 | 5.18±0.48* | 5.05±0.55* | 5.18±0.43* | 5.42±0.45* | 5.18±0.48* | 5.07±0.53* | 5.29±0.45* |
Female | 4.49±0.37 | 4.63±0.41* | 4.57±0.39* | 4.52±0.34 | 4.72±0.43* | 4.63±0.41* | 4.56±0.39* | 4.63±0.35 |
Hb, g/L | ||||||||
Male | 149.13±21.41 | 154.76±17.34* | 154.33±14.20 | 156.46±9.83* | 160.83±10.50* | 154.73±17.29* | 154.30±13.92* | 159.74±8.85* |
Female | 132.37±13.05 | 136.84±62.82 | 132.93±13.19* | 131.20±11.95* | 133.57±12.49* | 133.76±16.47* | 144.92±121.74 | 132.13±11.89* |
PLTs, 10/L | ||||||||
Male | 239.11±64.65 | 236.39±63.84 | 232.87±67.35 | 264.69±82.35 | 224.67±60.92 | 236.58±63.68 | 244.02±74.46 | 222.89±59.70 |
Female | 261.23±65.39 | 257.58±67.57 | 256.57±76.90* | 259.13±76.23* | 274.29±76.38 | 257.48±67.78 | 259.38±74.90 | 258.61±74.93* |
Neutrophils, 10/L | ||||||||
Male | 4.30±4.81 | 4.34±4.61 | 4.16±1.30 | 4.71±1.59 | 3.74±0.85 | 4.34±4.59 | 4.32±1.38* | 4.00±1.17 |
Female | 3.92±3.30 | 3.77±3.31 | 3.62±1.08 | 3.78±1.36 | 3.92±0.69 | 3.77±3.32 | 3.62±1.04 | 3.95±1.19 |
Lymphocytes, 10/L | ||||||||
Male | 1.91±0.60 | 1.73±0.59* | 1.67±0.56* | 1.58±0.81* | 1.66±0.60 | 1.73±0.58* | 1.73±0.65* | 1.38±0.43 |
Female | 2.09±1.61 | 1.85±1.32* | 1.66±0.59 | 1.65±0.55* | 1.70±0.48* | 1.85±1.32* | 1.67±0.60* | 1.67±0.53* |
Monocytes, 10/L | ||||||||
Male | 0.37±0.53 | 0.34±0.39 | 0.29±0.11 | 0.36±0.11 | 0.32±0.05 | 0.34±0.39 | 0.30±0.12 | 0.32±0.08 |
Female | 0.31±0.39 | 0.32±0.50 | 0.26±0.08 | 0.27±0.10 | 0.31±0.11* | 0.32±0.50 | 0.27±0.08 | 0.28±0.10 |
Hb – hemoglobin; PLT – platelet; RBC – red blood cell; SD – standard deviation; WBC – white blood cell. * a Indicates an increase and b a decrease. |