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24 March 2021: Clinical Research

Contribution of Interstitial Cells of Cajal to Gastrointestinal Stromal Tumor Risk

Qi Wang 1ABEG* , Zhen-peng Huang 2ACDEF** , Yu Zhu 3B , Fei Fu 1B , Lin Tian 1ABDG*

DOI: 10.12659/MSM.929575

Med Sci Monit 2021; 27:e929575

Table 1 The clinical and pathological characteristics of GIST patients.

Number/sizePercentage (%)/mean/median
 Very low risk4436.07
 Low risk2923.77
 Intermediate risk1613.11
 High risk3327.05
 Very low risk
 Low risk
 Intermediate risk
 High risk
 Very low risk37–7757.11±9.69
 Low risk31–7759.64±11.10
 Intermediate risk50–7863.44±8.68
 High risk40–8258.69±9.90
 Small intestine75.74
 Colon and rectum1411.47
 Omentum and mesentery108.20
 Small intestine3–148
 Colon and rectum0.8–128
# χ=2.4778, =0.0132;
* =−0.990, =0.327.
Most of GIST cases were very low-risk and low-risk. Male patients were more likely to have very low-risk and low-risk GISTs, whereas women were more likely to have high-risk GISTs (χ=2.4778, P=0.0132). Age at GIST diagnosis ranged from 31 to 82 years (58.69±9.90), but was not significantly associated with GIST risk (=−0.990, P=0.327). Most GISTs were located in the stomach. The size of tumors varied between 0.5 and 20 cm.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750