18 April 2021>: Animal Study
Left Ventricular Impaired Relaxation and Interstitial Myocarditis Identified in Sepsis-Associated Cardiac Dysfunction: Use of a Rodent Model
David J. Sturgess 1ABCDEFG* , Shannon Morrison 1BCDE , Brian Haluska 2BCD , Glenda C. Gobe 23BCDEG , Mark A. Jones 4ACDE , Sonia Volante 1BE , Bala Venkatesh 2ACDEGDOI: 10.12659/MSM.929512
Med Sci Monit 2021; 27:e929512
Table 2 Histopathology results for LPS model LV myocardium with HE staining.
Group | Marked hydropic change | Mild hydropic change | Moderate hydropic change | Total |
---|---|---|---|---|
Control (no.) | 0 | 4 | 3 | 7 |
(%) | 0.00 | 57.14 | 42.86 | |
Endotoxin (no.) | 5 | 0 | 2 | 7 |
(%) | 71.43 | 0.00 | 28.57 | |
Total | 5 | 4 | 5 | 14 |
Marked hydropic change was observed in five out of seven endotoxic animals, but was not present in any control animals, (P=0.015; Fisher exact). HE – hematoxylin and eosin staining. |