Overexpression of Apolipoprotein C1 (APOC1) in Clear Cell Renal Cell Carcinoma and Its Prognostic Significance

16 February 2021: Database Analysis

Huaying Xiao ^1CE , Yifang Xu ^2AE*

DOI: 10.12659/MSM.929347

Med Sci Monit 2021; 27:e929347

Table 2 Association of OS and clinical pathological characteristics in patients using Cox regression analysis.

	Univariate analysis			Multivariate analysis
	HR	95% CI	P-value	HR	95% CI	P-value
Age (≥60 vs	1.818	1.429–2.488		1.802	1.317–2.467
Sex (Female vs Male)	1.059	0.779–1.441	0.714	1.042	0.757–1.434	0.802
APOC1 expression (high vs low)	1.401	1.037–1.892	0.028	1.379	1.021–1.863	0.036
Clinical stage (III+IV vs I+II)	3.874	2.825–5.311		3.563	1.959–6.482
T stage (T3+T4 vs T1+T2)	2.868	2.065–3.981		0.796	0.426–1.488	0.475
Primary tumor laterality (right vs left)	0.717	0.532–0.966	0.029	0.803	0.594–1.084	0.152
Histological grade (G3+G4 vs G1+G2)	2.615	1.862–3.673		1.818	1.262–2.619	0.001
HR – hazard ratio, estimated from Cox proportional hazard regression model. CI – confidence interval of the estimated HR.