14 July 2021: Animal Study
Low Dose of Emodin Inhibits Hypercholesterolemia in a Rat Model of High Cholesterol
Jian-Hong Wu 1ABCDEF* , Chun-Fang Lv 1ABDE* , Xu-Jun Guo 1CDEF* , Huan Zhang 2CF , Jinde Zhang 1BD , Yangfeng Xu 1BD , Jian Wang 1AEG** , Sheng-Yuan Liu 1ACEFG***DOI: 10.12659/MSM.929346
Med Sci Monit 2021; 27:e929346
Table 1 Primer sequences.
| Gene | Orientation | Sequence (5′ to 3′) |
|---|---|---|
| eNOS | Forward | GGATTCTGGCAAGACCGATTAC |
| Reverse | GGTGAGGACTTGTCCAAACACT | |
| LDLR | Forward | TGGCTATGAGTGCCTATGTC |
| Reverse | GGTGAAGAGCAGAAACCCTA | |
| GAPDH | Forward | TGCACCACCAACTGCTTAG |
| Reverse | AGTGGATGCAGGGATGATGT | |
| eNOS – endothelial nitric oxide synthase; LDLR – low density lipoprotein receptor; GAPDH – glyceraldehyde-3-phosphate dehydrogenase. | ||