12 May 2021: Molecular Biology
Decreased HLF Expression Predicts Poor Survival in Lung Adenocarcinoma
Zaiyan Wang BE* , Xiaoning Li BE* , Hao Chen CF , Li Han CD , Xiaobin Ji BD , Qiubo Wang DF , Li Wei BF , Yafang Miao CF , Jing Wang F , Jianfeng Mao F , Zeming Zhang AG*DOI: 10.12659/MSM.929333
Med Sci Monit 2021; 27:e929333
Table 2 Functional and pathway enrichment analysis of the DEGs.
| Term | Name | Count | P value | Genes |
|---|---|---|---|---|
| GO: 0007155 | Cell adhesion | 17 | 9.7E-6 | |
| GO: 0001763 | Morphogenesis of a branching structure | 4 | 4.8E-5 | |
| GO: 0001525 | Angiogenesis | 10 | 3.2E-4 | |
| GO: 0005515 | Protein binding | 94 | 1.1E-2 | |
| GO: 0008289 | Lipid binding | 6 | 1.2E-2 | |
| GO: 0001077 | Transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding | 7 | 1.9E-2 | |
| GO: 0005887 | Integral component of plasma membrane | 29 | 7.7E-5 | |
| GO: 0045121 | Membrane raft | 10 | 1.2E-4 | |
| GO: 0005886 | Plasma membrane | 59 | 1.9E-4 | |
| hsa04512 | ECM-receptor interaction | 6 | 2.5E-3 | |
| Hsa04974 | Protein digestion and absorption | 5 | 1.5E-2 | |
| hsa04360 | Axon guidance | 5 | 4.9E-2 | |
| ECM – extracellular membrane; KEGG – Kyoto Encyclopedia of Genes and Genomes. When more than 3 enriched terms were identified in each category, the top 3 terms were selected according to value. | ||||