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12 May 2021: Molecular Biology

Decreased HLF Expression Predicts Poor Survival in Lung Adenocarcinoma

Zaiyan Wang BE* , Xiaoning Li BE* , Hao Chen CF , Li Han CD , Xiaobin Ji BD , Qiubo Wang DF , Li Wei BF , Yafang Miao CF , Jing Wang F , Jianfeng Mao F , Zeming Zhang AG*

DOI: 10.12659/MSM.929333

Med Sci Monit 2021; 27:e929333

Table 2 Functional and pathway enrichment analysis of the DEGs.

TermNameCountP valueGenes
GO: 0007155Cell adhesion179.7E-6
GO: 0001763Morphogenesis of a branching structure44.8E-5
GO: 0001525Angiogenesis103.2E-4
GO: 0005515Protein binding941.1E-2
GO: 0008289Lipid binding61.2E-2
GO: 0001077Transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding71.9E-2
GO: 0005887Integral component of plasma membrane297.7E-5
GO: 0045121Membrane raft101.2E-4
GO: 0005886Plasma membrane591.9E-4
hsa04512ECM-receptor interaction62.5E-3
Hsa04974Protein digestion and absorption51.5E-2
hsa04360Axon guidance54.9E-2
ECM – extracellular membrane; KEGG – Kyoto Encyclopedia of Genes and Genomes. When more than 3 enriched terms were identified in each category, the top 3 terms were selected according to value.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750