20 April 2021: Clinical Research
Overexpression of circ_0021739 in Peripheral Blood Mononuclear Cells in Women with Postmenopausal Osteoporosis Is Associated with Reduced Expression of microRNA-194-5p in Osteoclasts
Jiaxin Guan 1BCEF , Lu Gan 1B , Di Jin 1ACD , Xiaowei Wu 1B , Luyang Cheng 1C , Meiling Liu 1C , Ying Fan 1B , Jing Zhou 2B , Hanlu Zhang 1B , Yina Zhang 1AFG* , Ping Zhou 1FG*DOI: 10.12659/MSM.929170
Med Sci Monit 2021; 27:e929170
Table 1 Clinical characteristics of the participants.
| Characteristic | Control group (n=25) | PMOP group (n=28) | P value |
|---|---|---|---|
| Age, years | 57.00±5.19 | 59.50±4.37 | 0.063 |
| Height, cm | 161.80±5.02 | 159.27±4.21 | 0.052 |
| Weight, kg | 60.64±9.08 | 56.39±6.74 | 0.057 |
| BMI, kg/m | 23.11±2.99 | 22.22±2.37 | 0.233 |
| Lymphocyte count, 10/L | 2.09±0.61 | 1.70±0.62 | 0.137 |
| Monocyte count, 10/L | 0.32±0.18 | 0.26±0.12 | 0.103 |
| T-score | |||
| Lumbar vertebra | −0.31±0.61 | −3.10±0.66 | * |
| Femur | −0.24±0.60 | −2.74±0.52 | * |
| Forearm | −0.47±0.84 | −3.18±1.37 | * |
| BMD, g/cm | |||
| Lumbar vertebra | 1.003±0.066 | 0.709±0.064 | * |
| Femur | 0.813±0.076 | 0.556±0.066 | * |
| Forearm | 0.655±0.055 | 0.504±0.076 | * |
| Data are presented as mean±SD or median±quartile. * | |||