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30 April 2021: Clinical Research

Comparison of Different Hydration Strategies in Patients with Very Low-Risk Profiles of Contrast-Induced Nephropathy

Shuai Miao 1BCE , Zheng-Kai Xue 1B , Ya-Ru Zhang 1F , Hao Zhang 1A , Jing-Jin Che 1C , Tong Liu 1DF , Hua-Yue Tao 2C , Guangping Li 1AD* , Kang-Yin Chen 1ADG*

DOI: 10.12659/MSM.929115

Med Sci Monit 2021; 27:e929115

Table 1 Baseline characteristics of the 3 groups.

VariablesPreventive groupRemedial groupNH groupP value
Age, years63.22±7.1562.47±7.4462.85±7.290.88
Male gender, n (%)29 (59.18)21 (44.68)25 (52.08)0.36
Height, cm166.31±15.60165.94±7.94166.42±5.670.97
Weight, Kg70.84±11.3468.67±11.5170.33±9.420.59
BMI, Kg/m24.90±2.8424.87±3.2125.33±2.560.68
Systolic BP, mmHg133.45±16.32132.66±16.40137.35±13.260.28
Diastolic BP, mmHg79.00±11.0177.94±10.7777.88±8.830.83
HR, bpm68.92±9.9670.81±9.8969.33±8.750.59
CAG, n (%)25 (51.02)26 (55.32)26 (54.17)0.91
Contrast volume, ml89.69±41.6686.81±38.6786.87±40.330.92
 Hypertension, n (%)35 (71.43)27 (57.45)31 (64.58)0.36
 Stroke, n (%)3 (6.12)4 (8.51)1 (2.08)0.38
 Cigarette, n (%)20 (40.82)13 (27.66)13 (27.08)0.26
 Alcohol, n (%)6 (12.24)6 (12.77)6 (12.50)0.99
 LA, mm37.94±4.6436.29±3.9936.56±4.490.16
 LV-d, mm47.59±5.6345.97±4.7847.18±3.650.25
 EF, %61.59±5.0264.69±4.3163.95±9.380.07
 IVS, mm9.59±1.538.89±1.219.22±2.060.13
 Aspirin, n (%)48 (97.96)44 (93.62)46 (95.83)0.79
 Clopidogrel, n (%)43 (87.76)42 (89.36)43 (89.58)0.85
 β-block, n (%)29 (59.18)26 (55.32)31 (64.58)0.72
 CCB, n (%)20 (40.82)19 (40.43)16 (33.33)0.67
 ACEI/ARB, n (%)25 (51.02)17 (36.17)21 (43.75)0.39
 Statins, n (%)42 (85.71)39 (82.98)40 (83.33)0.95
 Nitrate, n (%)28 (57.14)25 (53.19)30 (62.50)0.72
 Hb, g/L141.55±12.43137.54±14.49139.69±13.520.35
 HCT, %41.08±6.5440.60±3.9241.22±3.600.81
 ALB, g/L43.15±2.9242.30±3.0343.02±3.130.34
 TG, mmol/L1.40±0.611.54±0.771.68±1.330.36
 TC, mmol/L4.29±0.964.62±1.004.66±1.110.16
 LDL-C, mmol/L2.67±0.832.82±0.752.88±0.960.46
 Glu, mmol/L5.33±0.675.30±0.535.42±0.670.65
 eGFR, mL/min/1.73 m87.02±21.4992.93±24.6492.43±22.910.38
 V/CrCl0.99±0.550.87±0.411.00±0.550.39
HR – heart rate; CAG – coronary arteriography; BMI – body mass index; LA – left atrial diameter; LV-d – left ventricular end diastolic diameter; EF – ejection fraction; IVS – interventricular septal; CCB – calcium channel blocker; ACEI – angiotensin converting enzyme inhibitors; ARB – angiotensin receptor blockers; Hb – hemoglobin; HCT – hematocrit; ALB – albumin; TG – total triglyceride; TC – total cholesterol; LDL-C – low density lipoprotein cholesterol; Glu – glucose; eGFR – estimated glomerular filtration rate; V/CrCl – ratio of contrast volume-to-creatinine clearance.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750