17 March 2021: Clinical Research
Different Doses of Oxycodone for Endoscopic Injection Sclerotherapy of Esophageal Varices
Jie Yao 1AEF* , ChunXiao Song 2BF* , Chen Zhou 3C , HaiLi He 4AEG* , ZheFeng Quan 4BDDOI: 10.12659/MSM.929111
Med Sci Monit 2021; 27:e929111
Table 2 Comparison of adverse effects among the 3 groups.
| Parameter | Group A (n=40) | Group B (n=40) | Group C (n=39) | P (Cochran-Armitage trend test) |
|---|---|---|---|---|
| Limb movement (%) | 13 (32.5)a | 5 (12.5) | 0 | |
| Hypoxia before EIS (%) | 6 (15.0),b | 3 (7.5) | 13 (33.3) | 0.026 |
| Hypoxia during EIS (%) | 9 (22.5) | 1 (2.5) | 0 | |
| Myoclonus (%) | 0 | 0 | 0 | 0.623 |
| Cough (%) | 0 | 0 | 1 (2.6) | 0.328 |
| Bradycardia (%) | 0 | 1 (2.5) | 2 (5.0) | 0.142 |
| Hypotension (%) | 0 | 2 (5.0.) | 2 (5.0) | 0.175 |
| Nausea and vomiting (%) | 3 (7.5) | 2 (5.0) | 5 (12.8) | 0.263 |
| Drowsiness (%) | 0 | 0 | 1 (2.6) | 0.328 |
| Dizziness (%) | 0 | 1 (2.5) | 0 | 0.664 |
| a b =0.014 vs Group B; c =0.002 vs Group C. | ||||