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10 April 2021: Clinical Research

Clinical Application of Chromosomal Microarray Analysis in Pregnant Women with Advanced Maternal Age and Fetuses with Ultrasonographic Soft Markers

Zhu-Ming Hu ABCE , Lei-Lei Li ABD , Han Zhang BF , Hong-Guo Zhang BC , Rui-Zhi Liu AFG , Yang Yu ACF*

DOI: 10.12659/MSM.929074

Med Sci Monit 2021; 27:e929074

Table 1 Clinical characteristics of the women compared among groups.

Clinical characteristicsAllGroup 1Group 2Group 3p
Number of cases1521633750138
Maternal age (year) (Mean±SD)33.27±5.5738.18±2.6628.42±3.0837.14±2.24
GA at amniocentesis (days) (Means±SD)141.63±19.86136.34±13.21146.26±23.33140.69±18.64
Pregnancy outcomes
 Ongoing/LB n (%)1464 (96.25)615 (97.16)719 (95.87)130 (94.20)>0.05
 TOP n (%)57 (3.75)18 (2.84)31 (4.13)8 (5.80)>0.05
SD – standard deviation; GA – gestational age; LB – live birth; TOP – termination of pregnancy.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750