10 April 2021>: Clinical Research
Clinical Application of Chromosomal Microarray Analysis in Pregnant Women with Advanced Maternal Age and Fetuses with Ultrasonographic Soft Markers
Zhu-Ming Hu ABCE , Lei-Lei Li ABD , Han Zhang BF , Hong-Guo Zhang BC , Rui-Zhi Liu AFG , Yang Yu ACF*DOI: 10.12659/MSM.929074
Med Sci Monit 2021; 27:e929074
Table 1 Clinical characteristics of the women compared among groups.
Clinical characteristics | All | Group 1 | Group 2 | Group 3 | p |
---|---|---|---|---|---|
Number of cases | 1521 | 633 | 750 | 138 | |
Maternal age (year) (Mean±SD) | 33.27±5.57 | 38.18±2.66 | 28.42±3.08 | 37.14±2.24 | |
GA at amniocentesis (days) (Means±SD) | 141.63±19.86 | 136.34±13.21 | 146.26±23.33 | 140.69±18.64 | |
Pregnancy outcomes | |||||
Ongoing/LB n (%) | 1464 (96.25) | 615 (97.16) | 719 (95.87) | 130 (94.20) | >0.05 |
TOP n (%) | 57 (3.75) | 18 (2.84) | 31 (4.13) | 8 (5.80) | >0.05 |
SD – standard deviation; GA – gestational age; LB – live birth; TOP – termination of pregnancy. |