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23 January 2021: Database Analysis

Correlation Between High Expression of and Improved Overall Survival in Ovarian Cancer Patients

Hui Shang 1FG , Lingyun Shi 2BC , Xuena Jiang 3CF , Peng Zhou 4CD , Yongqing Wei 1AB*

DOI: 10.12659/MSM.928763

Med Sci Monit 2021; 27:e928763

Table 1 Gene Ontology (GO) enrichment of FOXA2 and relevant genes.

DescriptionCountQ valueGene ratio
Endocrine system development241.75E-350.2
Positive regulation of transcription, DNA-templated421.75E-350.029268293
Positive regulation of macromolecule biosynthetic process441.75E-350.025028441
Positive regulation of transcription by RNA polymerase II392.23E-350.035326087
Positive regulation of gene expression442.64E-350.024096386
Positive regulation of cellular biosynthetic process443.02E-350.02383532
Positive regulation of RNA metabolic process421.32E-340.026315789
Regulation of transcription by RNA polymerase II451.64E-300.017090771
Pancreas development186.81E-280.25
Intracellular membrane-bounded organelle498.56E-100.004727
Transcription factor complex122.99E-090.03681
Intracellular organelle lumen351.72E-080.00678
Nuclear lumen306.12E-080.007444
Nuclear transcription factor complex74.32E-060.042169
RNA polymerase II transcription factor complex50.000410.035971
beta-catenin-TCF7L2 complex20.000710.666667
Nuclear chromatin60.00230.018018
Transcription regulatory region sequence-specific DNA binding344.06E-340.047887
Sequence-specific DNA binding377.06E-340.035339
Transcription regulatory region DNA binding357.06E-340.04222
RNA polymerase II regulatory region sequence-specific DNA binding313.21E-310.047913
DNA-binding transcription factor activity392.38E-290.022298
DNA-binding transcription factor activity, RNA polymerase II-specific385.07E-290.023299
DNA-binding transcription activator activity, RNA polymerase II-specific242.17E-250.058824
Proximal promoter sequence-specific DNA binding245.92E-240.050526
RNA polymerase II proximal promoter sequence-specific DNA binding237.84E-230.050328
DNA binding388.70E-230.015466

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750