02 December 2020: Clinical Research
A Retrospective Study on the Effects of Convalescent Plasma Therapy in 24 Patients Diagnosed with COVID-19 Pneumonia in February and March 2020 at 2 Centers in Wuhan, China
Shuang Huang C* , Changxin Shen B* , Chengliang Xia F , Xiaoxing Huang C , Yourong Fu A , Li Tian E*DOI: 10.12659/MSM.928755
Med Sci Monit 2020; 26:e928755
Table 3 The laboratory findings before and after convalescent plasma transfusion in 14 patients with COVID-19 pneumonia who had an effective response to this treatment.
| Laboratory indicators | Normal range | Before CP transfusion | After CP transfusion | P values |
|---|---|---|---|---|
| WBC, 10/L | 3.5–9.5 | 9.28 (6.91–10.96) | 8.84 (7.16–11.37) | 0.982 |
| Lymphocyte, 10/L | 1.1–3.2 | 0.80 (0.58–0.91) | 1.12 (0.87–2.11) | 0.004* |
| CRP, mg/L | 0–4 | 64.14 (32.85–96.10) | 26.08 (8.34–42.09) | 0.008* |
| PCT, ng/ml | 0–0.05 | 0.55 (0.19–1.71) | 0.31 (0.09–0.48) | 0.273 |
| ALT, IU/L | 7–45 | 30.50 (22.50–64.50) | 24.50 (12.00–39.25) | 0.175 |
| AST, IU/L | 13–35 | 37.50 (25.00–55.25) | 28.00 (22.50–40.00) | 0.375 |
| Urea, mmol/L | 3.1–8.8 | 7.90 (5.73–11.93) | 7.45 (3.85–15.53) | 0.581 |
| WBC – white blood cell; CRP – high-sensitivity C-reactive protein; PCT – procalcitonin; ALT – alanine aminotransferase; AST – aspartate transaminase; urea – urea nitrogen. * Indicated statistical significance ( | ||||