12 March 2021: Clinical Research
A Single-Center Prospective Study of 116 Women with Osteoporosis Treated with Zoledronic Acid Monitored by Electrocardiography for the Development of Cardiac Arrhythmia During the Acute Phase in China
HuaFeng Zhuang 1BCE , YiZhong Li 1ABC* , JinKuang Lin 1BCD , XueDong Yao 1CDF , YanYu Xie 2BCF , PeiWen Wang 1BDF , Hao Xu 1CDFDOI: 10.12659/MSM.928637
Med Sci Monit 2021; 27:e928637
Table 3 Comparison of ECG parameters before and after zoledronate administration.
| Before adminstration | After adminstration | t value | P value | |
|---|---|---|---|---|
| Heart rate | 75.2±12.2 | 79.7±13.7 | 3.232 | 0.002 |
| P wave max (ms) | 105.5±10.5 | 103.9±10.7 | 1.624 | 0.107 |
| P wave min (ms) | 78.7±11.7 | 76.8±12.2 | 1.761 | 0.081 |
| P wave dispersion (ms) | 26.7±9.2 | 27.1±8.7 | 0.385 | 0.701 |
| PR intervals, (ms) | 153.3±17.9 | 155.2±18.4 | 1.122 | 0.264 |
| QRS durations (ms) | 88.0±7.2 | 86.9±7.3 | 1.787 | 0.077 |
| QT (ms) | 382.6±29.4 | 373.4±33.3 | 2.823 | 0.006 |
| QTc max (ms) | 429.3±22.3 | 429.8±22.8 | 0.269 | 0.789 |
| QTc min (ms) | 397.3±22.6 | 399.2±21.1 | 0.972 | 0.333 |
| QTc dispersion (ms) | 32.0±11.5 | 30.7±10.2 | 1.073 | 0.286 |
| ECG – electrocardiograph. | ||||