A Single-Center Prospective Study of 116 Women with Osteoporosis Treated with Zoledronic Acid Monitored by Electrocardiography for the Development of Cardiac Arrhythmia During the Acute Phase in China

12 March 2021: Clinical Research

HuaFeng Zhuang ^1BCE , YiZhong Li ^1ABC* , JinKuang Lin ^1BCD , XueDong Yao ^1CDF , YanYu Xie ^2BCF , PeiWen Wang ^1BDF , Hao Xu ^1CDF

DOI: 10.12659/MSM.928637

Med Sci Monit 2021; 27:e928637

Table 2 Electrocardiogram findings of patients before and after zoledronate administration.

	Before zoledronate adminstration	After zoledronate adminstration	p
Normal ECG	47	35	0.099
Abnormal ECG	69	81	0.099
Sinus arrhythmia	13	13
Sinusal tachycardia	2	9
Sinusal bradycardia	9	2
Atrial premature	6	5
Ventricular premature	1	3
Atrial fibrillation/flutter	0	1
branch block	2	4
Atrioventricular block	0	1
Left ventricular hypertrophy	6	6
ST or T Wave change	30	37
ECG – electrocardiograph;