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07 March 2021: Clinical Research

Association of Leptin Receptor Gene Polymorphisms with Keloids in the Chinese Han Population

Jing Liu 1ABCD , Limin Cai 1CDEF , Zepeng Zhang 1BCD , Yanli Ma 1BCDF , Yongchen Wang 2ADE*

DOI: 10.12659/MSM.928503

Med Sci Monit 2021; 27:e928503

Table 3 The frequencies of genotypes and alleles in LEPR gene.

SNPKeloidNormal controlsP-valueOR (95% CI)
 GA6819.32%6622.07%0.3860.845 (0.578–1.237)
 GG27377.56%23177.26%0.9271.017 (0.704–1.471)
 AA113.13%20.67%0.0264.790 (1.053–21.785)
 G61487.22%52888.29%0.1050.760 (0.546–1.059)
 CT11131.53%9832.78%0.7350.945 (0.679–1.314)
 CC246.82%103.34%0.0472.115 (0.994–4.497)
 TT21761.65%19163.88%0.5570.909 (0.661–1.251)
 C15922.59%11819.73%0.2101.187 (0.908–1.551)
 GA8323.58%6120.40%0.3301.204 (0.828–1.749)
 GG25973.58%23177.26%0.2780.82 (0.572–1.175)
 AA102.84%72.34%0.6901.220 (0.458–3.245)
 G60185.37%52387.46%0.2740.837 (0.608–1.152)
 GA10830.68%6923.08%0.0301.475 (1.038–2.097)
 GG164.55%103.34%0.4351.376 (0.615–3.08)
 AA22864.77%22073.58%0.0160.660 (0.471–0.925)
 G14019.89%8914.88%0.0181.420 (1.061–1.900)
LEPR – leptin receptor; SNP – single nucleotide polymorphism; OR – odds ratio; CI – confidence interval; n – number.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750