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22 February 2021: Clinical Research

Fractional Exhaled Nitric Oxide (FeNO) Integrating Airway Hyperresponsiveness (AHR) Examination Promotes Etiologic Diagnosis and Treatment for Children with Chronic Cough

Haiyan Zhu 1BCDEF , Chuangli Hao 2BCDE , Xingmei Yu 2BCDF , Rongrong Zhang 1BCD , Wendi Zhou 1BCF , Xingzhen Sun 1BCF , Yufang Yuan 1BCF , Zhaofang Tian 1ABDEG*

DOI: 10.12659/MSM.928502

Med Sci Monit 2021; 27:e928502

Table 1 Comparisons for initial diagnosis of fractional exhaled nitric oxide (FeNO) and other parameters in children with chronic cough for different etiologies (χ±s).

ParametersCVA group (n=45)UACS group (n=53)PIC group (n=20)F/χ2P
FeNO35±14* 17±819±820.8100.000
EOS in sputum (%, median)6.5 (6)* 0.5 (1)0.5 (1.5)6.6880.001
Cough symptom score3.5±0.73.2±0.73.5±1.02.2240.090
CVA – cough-variant asthma; UACS – upper-airway cough syndrome; PIC – post-infection cough.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750