03 March 2021>: Animal Study
A Network Pharmacology Study of the Molecular Mechanisms of in the Treatment of Cholestatic Hepatitis with Validation in an Alpha-Naphthylisothiocyanate (ANIT) Hepatotoxicity Rat Model
Sen Ling Feng 1ACE* , Jing Zhang 2BCEF* , Hongliu Jin 1BC , Wen Ting Zhu 1BC , Zhongwen Yuan 1ABCDEFG*DOI: 10.12659/MSM.928402
Med Sci Monit 2021; 27:e928402
Table 2 The active components of Hypericum japonicum.
MOL ID | Molecule name | MW | OB% | DL |
---|---|---|---|---|
MOL000069 | Palmitic acid | 256.48 | 19.3 | 0.1 |
MOL000098 | Quercetin | 302.25 | 46.43 | 0.28 |
MOL000105 | Protocatechuic acid | 154.13 | 25.37 | 0.04 |
MOL000114 | Vanillic acid | 168.16 | 35.47 | 0.04 |
MOL000166 | ZINC01609418 | 222.41 | 21.62 | 0.07 |
MOL000193 | (Z)-caryophyllene | 204.39 | 30.29 | 0.09 |
MOL000211 | Mairin | 456.78 | 55.38 | 0.78 |
MOL000358 | beta-sitosterol | 414.79 | 36.91 | 0.75 |
MOL000359 | Sitosterol | 414.79 | 36.91 | 0.75 |
MOL000414 | Caffeate | 180.17 | 54.97 | 0.05 |
MOL000422 | Kaempferol | 286.25 | 41.88 | 0.24 |
MOL000437 | Hirsutrin | 464.41 | 1.86 | 0.77 |
MOL000676 | DBP | 278.38 | 64.54 | 0.13 |
MOL000701 | Quercitrin | 448.41 | 4.04 | 0.74 |
MOL000861 | Healip | 326.68 | 11.65 | 0.22 |
MOL001955 | Heriguard | 354.34 | 11.93 | 0.33 |
MOL002067 | Hypericin | 504.46 | 14.66 | 0.08 |
MOL002378 | UND | 156.35 | 17.15 | 0.02 |
MOL002622 | Filicin | 668.8 | 6.71 | 0.63 |
MOL003228 | Norathyriol | 260.21 | 18.35 | 0.22 |
MOL004459 | Tridecanol | 200.41 | 15.18 | 0.04 |
MOL004746 | (E,7S,11R)-3,7,11,15-tetramethylhexadec-2-en-1-ol | 296.6 | 33.82 | 0.13 |
MOL004783 | Nonane | 128.29 | 29.23 | 0.01 |
MOL005810 | Lauryl palmitate | 424.84 | 14.45 | 0.43 |
MOL006771 | Poriferasterol monoglucoside | 574.93 | 21.32 | 0.63 |
MOL006772 | Poriferasterol monoglucoside_qt | 412.77 | 43.83 | 0.76 |
MOL007860 | Quercetin-7-rhamnoside | 448.41 | 15.5 | 0.76 |
MOL007861 | Sarothralin | 534.65 | 4.24 | 0.72 |
MOL007862 | Uliginosin B | 498.62 | 28.1 | 0.73 |
MOL007863 | Saroaspidin A | 446.54 | 5.74 | 0.48 |
MOL007864 | Saroaspiden B | 460.57 | 21.45 | 0.52 |
MOL007865 | Saroaspiden C | 474.6 | 5.57 | 0.55 |
MOL007866 | Japonicin A | 460.57 | 15.8 | 0.5 |
MOL007867 | Japonicine B | 566.75 | 3.92 | 0.78 |
MOL007868 | Japonicine C | 534.65 | 4.22 | 0.72 |
MOL007869 | Japonicine D | 668.8 | 1.6 | 0.64 |
MOL007870 | Sarothralen A | 568.77 | 0.97 | 0.69 |
MOL007871 | Sarothralin G | 602.78 | 0.96 | 0.7 |
MOL007872 | Quercetin-7-O-rhamnoside | 448.41 | 2.6 | 0.76 |
MOL007873 | Isoamyl laurate | 270.51 | 23.92 | 0.11 |
MOL007874 | Lauryl stearate | 452.9 | 13.92 | 0.46 |
MOL007875 | Mesylmethane | 94.15 | 40.12 | 0.00 |
MOL007876 | 2,4-dimethylheptane | 128.29 | 35.9 | 0.01 |
MOL007877 | n-Tetra-triacontanoic acid | 530.69 | 10.54 | 0.5 |
MOL007878 | 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-3-(alpha-D-galactopyranosyloxy)-5,7-dihydroxy- | 464.41 | 2.41 | 0.77 |
MOL007879 | Tetramethoxyluteolin | 342.34 | 43.68 | 0.37 |
MOL007880 | 3,5,7,3′,5′ pentahydroxy flavonol | 290.29 | 63.64 | 0.24 |
MOL007881 | 1,3,5,6-tetrahydroxyxanthone | 260.21 | 16.22 | 0.22 |
MOL007882 | Xanthone der. | 244.21 | 18.16 | 0.19 |