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29 May 2021: Lab/In Vitro Research

Silencing Ribosomal Protein L22 Promotes Proliferation and Migration, and Inhibits Apoptosis of Gastric Cancer Cells by Regulating the Murine Double Minute 2-Protein 53 (MDM2-p53) Signaling Pathway

Zhenqing Sun 1ABCE* , Zhigang Qiu 1ABCE* , Zhengkun Wang 1DE , Honghui Chi 2DE , Peipei Shan 3CE*

DOI: 10.12659/MSM.928375

Med Sci Monit 2021; 27:e928375

Table 2 Correlation between the expression of RPL22 and clinicopathological features of gastric cancer patients.

ParameterNumber (N=40)RPL22 mRNA expressionP value
Age (years)
 Early stage290.7370±0.06920.0372*
 Advanced stage110.4883±0.0347
Lymphatic metastasis
Tumor position
 Gastric fundus50.6793±0.1779
 Gastric angle70.7046±0.0686
Degree of histological type
RPL22 – ribosomal proteins L22;
* represented significantly different at

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750