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16 February 2021: Animal Study

Effects of Diabetes Mellitus on Sperm Quality in the Db/Db Mouse Model and the Role of the FoxO1 Pathway

Jisheng Wang 12ABDE* , Binghao Bao 12ABE* , Junlong Feng 12ABCE* , Qi Zhao 12BCF* , Hengheng Dai 12BDF , Fanchao Meng 12BF , Sheng Deng 12DF , Bin Wang 2AG* , Haisong Li 2AE*

DOI: 10.12659/MSM.928232

Med Sci Monit 2021; 27:e928232

Table 2 Top 10 key targets.

RankTarget nameScore
1Insulin (INS)29
2Interleukin 6 (IL-6)26
3Tumor protein P53 (TP53)25
4Insulin like growth factor 1 (IGF1)24
4AKT serine/Threonine kinase 1 (AKT1)24
6Leptin (LEP)23
6Albumin (ALB)23
8Tumor necrosis factor (TNF)22
9HRas Proto-Oncogene, GTPase (HRAS)20
9Proopiomelanocortin (POMC)20

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750