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18 January 2021: Clinical Research

Urinary Alpha1-Microglobulin: A New Predictor for In-Hospital Mortality in Patients with ST-Segment Elevation Myocardial Infarction

Hehe Cui 1ABCDE , Xiao Zhang 2CDE , Xiaosong Ding 1ABE , Li Zhou 1ADE , Siwen Liang 1AF , Hui Qiu 1CF , Hongwei Li 1ABFG , Hui Chen 1ADEG*

DOI: 10.12659/MSM.927958

Med Sci Monit 2021; 27:e927958

Table 2 In-hospital outcomes, myocardial injuries, and left ventricular function of STEMI patients based on the tertiles of UA1MG.

CharacteristicsTertile 1, n=623<0.77Tertile 2, n=6110.77–1.89Tertile 3, n=620>1.89p1 valuep2 value
In-hospital death, %6 (1.0)10 (1.7)27 (4.4)
Cardiac death, %4 (0.6)10 (1.7)19 (3.1)0.0050.001
MACE, %29 (4.7)31 (5.1)53 (8.6)0.0070.005
Cardiac markers
 Peak NTproBNP, pg/mL1164.0 (503.0–2706.0)1613.0 (701.0–3907.0)3825.0 (1639.5–9982.0)
 Peak CK-MB, ng/mL74.7 (11.9–202.0)95.9 (17.7–215.0)100.0 (21.1–273.8)0.0010.004
 Peak cTnI, ng/mL10.9 (2.5–28.7)15.1 (4.0–37.7)23.9 (7.2–50.0)
Categorical variable was presented as percentage and numeric variable was presented as mean±standard deviation or the median (interquartile range). P1 value was obtained from comparing three subgroups. P2 value was obtained from comparing the tertile 3 subgroup with the tertile 1 subgroup. MACE – major adverse cardiac events; CK-MB – creatine kinase MB; cTnI – cardiac troponin I; NT-proBNP – N-terminal pro-B-type Natriuretic Peptide; LVEF – left ventricular ejection fraction; UA1MG – urinary alpha1-microglobulin.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750