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21 January 2021: Database Analysis

Norepinephrine, Dopamine, and Vasopressin in Patients with Sepsis and Preexisting or Acute Heart Failure: A Retrospective Cohort Study

Dandan Zhou 1ABCEF** , Baohua Zhu 2ABCDF* , Jie Jiang 2DEF , Guangquan Zhou 3CEF , Suming Zhou 4ADEF*

DOI: 10.12659/MSM.927716

Med Sci Monit 2021; 27:e927716

Supplementary Table 2 Multiple linear regression analysis of MV duration in the NE, NE+VAS, VAS, and dopamine groups.

ParameterUnivariate (n=1909)Multivariate (n=1909, stepwise elimination)
Unstandardized B95% CIP valueUnstandardized B95% CIP value
Sex (Male)6.717−12.781~26.2140.499
Weight (kg)0.7250.354~1.096
Race (White)−16.6−38.426~5.2270.136
Group (NE reference)0.000
Lactate (mmol/L)2.815−2.181~7.8110.269
Bilirubin (mg/dL)1.754−0.959~4.4670.205
Platelets (k/μL)0.005−0.074~0.0830.909
sCr (μmol/L)−7.817−13.984~−1.6500.013
Heart rate (bpm)0.5260.019~1.0340.042
Preexisting HF−30.491−94.637~33.6560.351
APS-III – Acute Physiology Score III; BUN – blood urea nitrogen; CHF – congestive heart failure; GCS – Glasgow Coma Score; HF – heart failure; MV – mechanical ventilation; NE – norepinephrine; sCR – serum creatinine; SOFA – Sequential Organ Failure Assessment; VAS – vasopressin.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750