02 January 2021: Clinical Research
Association Between Thyroid Function and Body Composition in Type 2 Diabetes Mellitus (T2DM) Patients: Does Sex Have a Role?
Lu Chen 12ABCDEFG* , Min Zhang 2BCF , Shoukui Xiang 1BCF , Xiaohong Jiang 1BCD , Hongliu Gu 2CF , Qi Sha 2CD , Meidi Qu 2D , Ting Xu 3AEG*DOI: 10.12659/MSM.927440
Med Sci Monit 2021; 27:e927440
Table 1 Comparison of general data between male and female groups before propensity score matching.
| Group | Female groupN=230 | Male groupN=331 | P value |
|---|---|---|---|
| Age (years) | 59.2±12.3 | 56.4±12.3 | 0.009 |
| Height (cm) | 159.2±4.8 | 171.1±5.4 | |
| Weight (kg) | 62.1±11.5 | 72.5±11.3 | |
| BMI (kg/m) | 24.4±3.9 | 24.7±3.6 | 0.354 |
| Systolic pressure (mmHg) | 138.7±18.7 | 135.4±16.6 | 0.029 |
| Diastolic pressure (mmHg) | 82.4±9.6 | 84.3±10.8 | 0.033 |
| Disease course (years) | 9.0±7.7 | 7.3±6.4 | 0.003 |
| Fasting blood glucose (mmol/L) | 8.5±2.5 | 8.6±2.5 | 0.834 |
| Fasting C-peptide (pmol/L) | 1.9±1.1 | 2.0±1.2 | 0.412 |
| Modified HOMA-IR | 3.4±1.1 | 3.5±1.3 | 0.302 |
| Modified HOMA-islet | 43.7±38.7 | 47.2±47.5 | 0.371 |
| HbA1c (%) | 9.6±2.4 | 9.9±4.3 | 0.349 |
| Uric acid (μmol/L) | 270.8±87.8 | 316.6±91.4 | |
| Total cholesterol (mmol/L) | 4.7±1.1 | 4.5±1.2 | 0.031 |
| Triacylglycerol (mmol/L) | 2.2±1.9 | 2.5±2.6 | 0.237 |
| High-density lipoprotein (mmol/L) | 1.1±0.3 | 1.0±0.2 | |
| Low-density lipoprotein (mmol/L) | 2.5±0.7 | 2.3±0.8 | 0.010 |
| Results in the table: Mean±SD/N (%).BMI – body mass index; HOMA-IR – homeostasis model assessment for insulin resistance; HOMA-islet – homeostasis model assessment for islet beta-cell function; HbA1c – hemoglobin A1c. | |||