05 November 2020: Lab/In Vitro Research
Integrated Bioinformatics Analysis of Hub Genes and Pathways Associated with a Compression Model of Spinal Cord Injury in Rats
Chang Jiang BCE* , Zheng Li BCE* , Zhaoyi Wu DEF* , Yun Liang CD , Lixia Jin BD , Yuanwu Cao CG , Shengcheng Wan DG , Zixian Chen AG*DOI: 10.12659/MSM.927107
Med Sci Monit 2020; 26:e927107
Table 1 Top 3 up or down genes by comparing average FPKM between different days post-injury and Sham group.
| Up | Down | |||||
|---|---|---|---|---|---|---|
| Gene | Log2(FC) | FDR | Gene | Log2(FC) | FDR | |
| 1 d Sham | 4.26 | 0.02 | −3.86 | 0.00 | ||
| 3.81 | 0.04 | −4.5 | 0.00 | |||
| 3.49 | 0.00 | −5.04 | 0.07 | |||
| 3 d Sham | 1.16 | 0.04 | −0.98 | 0.01 | ||
| 0.99 | 0.04 | −1.09 | 0.03 | |||
| 0.74 | 0.03 | −1.16 | 0.03 | |||
| 5 d Sham | 2.54 | 0.03 | −1.36 | 0.02 | ||
| 2.12 | 0.03 | −1.6 | 0.04 | |||
| 2.04 | 0.04 | −2.22 | 0.03 | |||
| 7 d Sham | 3.66 | 0.01 | −5.63 | 0.02 | ||
| 3.25 | 0.02 | −6.42 | 0.01 | |||
| 2.95 | 0.03 | −6.74 | 0.01 | |||
| Log2(FC) – log2 fold change; FDR – adjusted values obtained applying the Benjamini-Hochberg method. | ||||||